Facilitation of colon cancer screening based on multi-energy CT colonography

• Project/Area Number: 15K12562
• Research Category: Grant-in-Aid for Challenging Exploratory Research
• Allocation Type: Multi-year Fund
• Research Field: Medical systems
• Research Institution: Oshima National College of Maritime Technology
• Principal Investigator: Tachibana Rie 大島商船高等専門学校, その他部局等, 准教授 (90435462)
• Research Collaborator: YOSHIDA Hiroyuki Massachusetts General Hospital, 3D Imaging Research, Director ; NÄPPI Janne J. Massachusetts General Hospital, 3D Imaging Research
• Project Period (FY): 2015-04-01 – 2018-03-31
• Project Status: Completed (Fiscal Year 2017)
• Budget Amount: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000); Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000); Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000); Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
• Keywords: Dual energy CT / CTコロノグラフィ / 機械学習

Outline of Final Research Achievements

The goal of this research was to develop and evaluate an innovative colon cancer screening system based on multi-energy CT colonography images and machine-learning-based segmentation methods of residual fecal materials. Preliminary results suggest that the multi-energy based electronic cleansing (EC) method is effective and that it minimizes the EC artifacts that were present in the single-energy based EC methods.

Research Products

• [Int'l Joint Research] Massachusetts General Hospital/Harvard Medical School(米国)
• [Int'l Joint Research] Massachusetts General Hospital/Harvard Medical School(米国)
• [Int'l Joint Research] Massachusetts General Hospital/Harvard Medica School(米国)
• [Journal Article] Transfer-learning deep convolutional neural network for classification of polyp candidates on CT colonography (2017)
  • Author(s): 植村 知規, 陸 慧敏, 金 亨燮, 橘 理恵, 弘 中亨, Nappi Janne J., 吉田 広行
  • Journal Title: Medical Imaging and Information Sciences Volume: 34 Issue: 2 Pages: 80-86
  • DOI: 10.11318/mii.34.80
  • NAID: 130006846731
  • ISSN: 0910-1543, 1880-4977
  • Peer Reviewed / Int'l Joint Research
• [Presentation] Electronic cleansing for CT colonography using spectral-driven iterative reconstruction (2017)
  • Author(s): Radin A. Nasirudin, Janne J. Nappi, Toru Hironaka, Rie Tachibana, Hiroyuki Yoshida
  • Organizer: SPIE Medical Imaging 2017
  • Place of Presentation: Renaissance Orlando at Sea World/Orlando, Florida, USA
  • Year and Date: 2017-02-11
  • Int'l Joint Research
• [Presentation] Multislice ensemble deep learning of electronic cleansing for computeraided detection of colonic lesions in multispectral CT colonography (2017)
  • Author(s): Rie Tachibana, Janne J. Nappi, Toru Hironaka, Se Hyung Kim, Hiroyuki Yoshida
  • Organizer: Computer Assisted Radiology and Surgery Proceedings of the 31st International Congress and Exhibition (CARS2017)
  • Int'l Joint Research
• [Presentation] Performance Evaluation of Machine-Learning-based Electronic Cleansing Schemes for Ultra-Low-Dose Dual-energy CT Colonography (2016)
  • Author(s): Junko Ota, Rie Tachibana, Janne J. Nappi, Toru Hironaka, Daniele Regge, Hiroyuki Yoshida
  • Organizer: The 102nd Scientific Assembly and Annual Meeting of Radiological Society of North America (RSNA 2016)
  • Place of Presentation: McCormick Place, Chicago, USA
  • Year and Date: 2016-11-27
  • Int'l Joint Research
• [Presentation] Radiomic machine learning of electronic cleansing for ultra-low-dose dual-energy CT colonography (2016)
  • Author(s): Rie Tachibana, Junko Ota, Janne J. Nappi, Daniele Regge, Toru Hironaka, Hiroyuki Yoshida
  • Organizer: The Computer Assisted Radiology and Surgery 30th International Congress and Exhibition 2016 (CARS 2016)
  • Place of Presentation: Heidelberg Convention Center, German
  • Year and Date: 2016-06-21
  • Int'l Joint Research
• [Presentation] Deep learning for electronic cleansing in dual-energy CT colonography (2016)
  • Author(s): Rie Tachibana, Janne J. Nappi, Toru Hironakaa, Se Hyung Kim, Hiroyuki Yoshida
  • Organizer: Proceedings of SPIE, Medical Imaging
  • Place of Presentation: Town & Country Resort and Convention Center, San Diego, USA
  • Year and Date: 2016-02-27
  • Int'l Joint Research
• [Presentation] Performance evaluation of multi-material electronic cleansing for ultra-low-dose dual-energy CT colonography (2016)
  • Author(s): Rie Tachibana, Naja Kohlhase, Janne J. Nappi, Toru Hironaka, Junko Ota, Takayuki Ishida, Daniele Regge, Hiroyuki Yoshida
  • Organizer: Proceedings of SPIE, Medical Imaging
  • Place of Presentation: Town & Country Resort and Convention Center, San Diego, USA
  • Year and Date: 2016-02-27
  • Int'l Joint Research
• [Presentation] Machine Learning of Multi-material Electronic Cleansing for Dual-energy CT Colonography (2015)
  • Author(s): R. Tachibana, J.J. Nappi,N. Kohlhase, J. Ota, S.H. Kim, T. Hironaka, H. Yoshida
  • Organizer: Radiological Society of North America
  • Place of Presentation: McCormick Place, Chicago, USA
  • Year and Date: 2015-11-29
  • Int'l Joint Research
• [Presentation] Multi-material Electronic Cleansing for Non-cathartic Ultra-Low-Dose Dual-Energy CT Colonography (2015)
  • Author(s): N. Kohlhase, R. Tachibana, J.J. Nappi, J. Ota, D. Regge, T. Hironaka, H. Yoshida
  • Organizer: Radiological Society of North America
  • Place of Presentation: McCormick Place, Chicago, USA
  • Year and Date: 2015-11-29
  • Int'l Joint Research
• [Presentation] Machine-learning Electronic Cleansing for CT Colonography (2015)
  • Author(s): R. Tachibana, J.J. Nappi,N. Kohlhase, S.H. Kim, D. Rdgge, T. Hironaka, J. Ota, H. Yoshida
  • Organizer: Radiological Society of North America
  • Place of Presentation: McCormick Place, Chicago, USA
  • Year and Date: 2015-11-29
  • Int'l Joint Research