Electrophysiological inspection of improvement of somatic hyperalgesia and gastrointestinal paresthesia by physical exercise
| Project/Area Number |
15K12586
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Rehabilitation science/Welfare engineering
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| Research Institution | Saitama Prefectural University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
田山 淳 長崎大学, 教育学部, 准教授 (10468324)
原 元彦 埼玉県立大学, 保健医療福祉学部, 教授 (30386007)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 過敏性腸症候群 / 体性知覚過敏 / 運動療法 / 活動量 / リハビリテーション / 生活習慣 / 感作 / ストレス / 体性感覚 / 内臓知覚 / 運動介入 / 消化器 / 運動誘発電位 |
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| Outline of Final Research Achievements |
Irritable bowel syndrome (IBS) is characterized by central nervous system to processing visceral and somatic information recurrent abdominal pain and altered bowel habit. IBS symptom is known to reduce by exercise intervention. This study was tested effect of exercise for 4-week in 18 people with IBS and 10 asymptomatic participants and inspected the hypothesis that improvement and the desensitization of gastrointestinal symptoms produced. Results of gastrointestinal symptoms were significantly improved in high-locomotor activity group (more than 1,000 steps/day) than low-locomotor group. There were no significantly changes in somatic perception by exercise intervention in the both group. No difference of somatic perception was found on behalf of the difference in gastrointestinal symptom kept a 4-week momentum than 7,000 steps in IBS. These mechanisms should be demonstrated by analysis of the visceral and somatic information processing in human brain.
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Report
(4 results)
Research Products
(14 results)
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[Journal Article] Differential activation in amygdala and plasma noradrenaline during colorectal distention by administration of corticotropin-releasing hormone between healthy individuals and patients with irritable bowel syndrome.2016
Author(s)
Tanaka Y, Kanazawa M, Kano M, Morishita J, Hamaguchi T, Van Oudenhove L, Ly HG, Dupont P, Tack J, Yamaguchi T, Yanai K, Tashiro M, Fukudo S.
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Journal Title
PLoS One
Volume: 11
Issue: 7
Pages: 1-13
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Serotonin Transporter Gene Polymorphism Modulates Activity and Connectivity within an Emotional Arousal Network of Healthy Men during an Aversive Visceral Stimulus.2015
Author(s)
Kilpatrick LA, Mayer EA, Labus JS, Gupta A, Hamaguchi T, Mizuno T, Komuro H, Kano M, Kanazawa M, Aoki M, Fukudo S.
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Journal Title
PLoS One
Volume: 10
Issue: 4
Pages: 1-15
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research
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