| Project/Area Number |
15K12659
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Sports science
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| Research Institution | Niigata University of Health and Welfare |
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Principal Investigator |
Maruyama Atsuo 新潟医療福祉大学, 健康科学部, 教授 (80117548)
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| Co-Investigator(Kenkyū-buntansha) |
峠 哲男 香川大学, 医学部, 教授 (80197839)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 最大筋力増大 / 磁気刺激 / 1.5ms 刺激間隔 / 最大筋力トレーニング / 運動野皮質内抑制低下 / 運動野皮質内促通増加 / 神経可塑性 / PAS刺激 / 最大筋力 / 短間隔皮質内抑制 / 短間隔皮質内促通 / 筋力増強 / ２重TMS刺激 / 1.5msec 刺激間隔 / 2.0msec 刺激間隔 / 最大筋力の増大 / 神経可塑的変化 / 最大筋力増強 / 経頭蓋磁気刺激 / 短間隔運動皮質内抑制 / 短間隔運動皮質内促通 / 神経活性増大 |
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| Outline of Final Research Achievements |
Pinch force MVC can be increased by muscle hypertrophy and by improved recruitment of volitional drive from motor cortex. We examined whether brief excitability of corticospinal output induced by two pair pulses (1.5ms /2.0 ms ISI) /single pulse of 100%RMT TMS and by pre PAS for 15min (0.2 Hz) would improve MVC more effectively than training alone. 5 groups of subjects trained on 4 alternate days. They performed 4 brief sets of MVC training by 5min rest. Each set consisted of 3 MVCs (2s duration) by 1min rest. SICI and SICF were assessed before the start of the first and after the end of the last training sessions.
Training with superimposed 1.5ms TMS pulses increased pinch MVC more than in other groups. SICI and SICF were significantly less and more effects by the training in only 1.5ms TMS group, respectively. There was no change in either measure in other groups. Brief excitability by good ISI weak TMS during MVC training is an effective way of improving central drive to muscles.
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