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Whether the molecular hydrogen improve endurance performance by decreasing oxidative stress?

Research Project

Project/Area Number 15K12674
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Sports science
Research InstitutionWaseda University

Principal Investigator

Muraoka Isao  早稲田大学, スポーツ科学学術院, 教授 (80112712)

Co-Investigator(Renkei-kenkyūsha) Higashida Kazuhiko  滋賀県立大学, 人間文化学部, 准教授 (50634466)
Ikemura Tsukasa  横浜商科大学, 商学部, 専任講師 (00735433)
Research Collaborator Kawamura Takuji  早稲田大学, スポーツ科学学術院, 助教 (80823327)
Fujii Ryosuke  早稲田大学, スポーツ科学研究科
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords水素 / 活性酸素種 / 持久性パフォーマンス / ラット / グリコーゲン含量 / 酸化ストレス / 抗酸化 / 筋損傷 / ダウンヒル運動 / グリコーゲン / 持久的パフォーマンス / 抗酸化物質
Outline of Final Research Achievements

The purpose of this research was to obtain basic knowledge for application of molecular hydrogen (H2), which is attracting attention as a new antioxidant agent in recent years, in the health and sports science field. As a result of this study, there was no effect of H2 intake on exercise-induced oxidative stress, and endurance performance. However, it was shown that H2 significantly suppresses the decrease in liver glycogen content during endurance exercise.
These evidences suggest that intake of H2 suppresses the utilization of liver glycogen during exercise via physiological action other than antioxidation. Further research is needed on the mechanism that H2 suppressed the utilization of liver glycogen.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (3 results)

All 2018 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (2 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Effects of Exhaustive Exercises, with Different Intensities, on Oxidative Stress Markers in Rat Plasma and Skeletal Muscle2018

    • Author(s)
      Kawamura T, Fujii R, Higashida K, Muraoka I
    • Journal Title

      Science & Sports

      Volume: 33 Issue: 3 Pages: 169-175

    • DOI

      10.1016/j.scispo.2017.08.008

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] Hydrogen water suppresses skeletal muscle and liver glycogenolysis during exercise while does not affect oxidative stress, blood energy substrate and endurance performance in rats2017

    • Author(s)
      Kawamura T, Fujii R, Higashida K, Muraoka I
    • Organizer
      European College of Sports Science
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 負荷の異なる強制トレッドミル運動がラット血漿および骨格筋の酸化ストレスに及ぼす影響2016

    • Author(s)
      河村拓史、藤井亮輔、李茜、東田一彦、村岡功
    • Organizer
      第71回日本体力医学会大会
    • Place of Presentation
      岩手県・いわて県民情報交流センター(アイーナ)
    • Year and Date
      2016-09-24
    • Related Report
      2016 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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