Research Project
Grant-in-Aid for Challenging Exploratory Research
We investigated whether microRNAs is associated with features of high-functioning autism spectrum disorders(ASD).42 subjects with ASD and 127 age- and IQ-matched typically developing controls underwent blood sampling and their microRNAs were analyzed.Relative to TD controls,subjects with ASD showed significantly lower microRNAs expressions.We examined visual attention using an eye tracking system in infants(6-90 months of age)and measured the concentration of oxytocin(OT)in saliva samples.We observed a negative association between age and both attention toward social cues and salivary OT levels,and a positive association between age and attention for non-social cues.Our results suggest that there is an age-dependent association between visual attention for social cues and OT levels in infants and children, and that the development of visual attention to the eyes as social cues is associated with both OXTR polymorphisms and OT levels.These variations contribute to heterogeneity in ASD.
All 2017 2016 2015
All Journal Article (23 results) (of which Int'l Joint Research: 4 results, Peer Reviewed: 13 results, Open Access: 23 results, Acknowledgement Compliant: 6 results) Presentation (44 results) (of which Int'l Joint Research: 7 results, Invited: 3 results) Book (6 results) Patent(Industrial Property Rights) (1 results)
PLoS One
Volume: 12(1) Issue: 1 Pages: e0170096-e0170096
10.1371/journal.pone.0170096
Translational Psychiatry
Volume: 6 Issue: 8 Pages: e872-e872
10.1038/tp.2016.152
120007129377
Neuroimage: Clinical, 12: 600-606, 2016.
Volume: 12 Pages: 600-606
10.1016/j.nicl.2016.09.016
Scientific Reports
Volume: 6 Issue: 1 Pages: 37875-37875
10.1038/srep37875
120005890337
Child Psychiatry Hum Dev
Volume: 7(6) Issue: 5 Pages: 841-851
10.1007/s10578-016-0704-x
Neuroendocrinol Lett
Volume: 37(6) Pages: 439-444
小児内科
Volume: 48(2) Pages: 149-153
日本健康相談活動学会誌
Volume: 11巻1号 Pages: 3-4
薬学雑誌
Volume: 136巻5号 Pages: 711-714
精神科治療学(特集「こころの病理をさかのぼる-精神医学における乳幼児期の意義-」)
Volume: 31巻7号 Pages: 865-871
FOUR WINDS 乳幼児精神保健学会誌
Volume: 第9号 Pages: 10-17
『子育て支援と心理臨床』福村出版vol12
Volume: 9月号 Pages: 94-97
小児科臨床
Volume: 第69巻第10号 Pages: 1613-1622
40020936589
日本小児禁煙研究会雑誌
Volume: 6巻2号 Pages: 3-9
児童青年精神医学とその近接領域(特集・「子ども虐待とケア」)
Volume: 57巻5号 Pages: 31-37
130006865838
精神神経学雑誌
Volume: 117巻11号 Pages: 928-935
Molecular Autism
Volume: 7 Issue: 1 Pages: 19-19
10.1186/s13229-016-0083-y
Volume: 7 Issue: 1 Pages: 6-6
10.1186/s13229-016-0071-2
Clin Psychopharmacology Neurosci,
Volume: 14 Issue: 1 Pages: 79-87
10.9758/cpn.2016.14.1.79
Res Autism Spectr Disord,
Volume: 13-14 Pages: 1-7
10.1016/j.rasd.2014.12.011
Volume: 10 Issue: 11 Pages: e0143126-e0143126
10.1371/journal.pone.0143126
120005756532
World Journal of Biological Psychiatry
Volume: 18 Issue: 4 Pages: 1-7
10.3109/15622975.2015.1102325
Brain Dev
Volume: S0387-7606 Issue: 5 Pages: 00235-1
10.1016/j.braindev.2015.11.005