| Project/Area Number |
15K12771
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Basic / Social brain science
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| Research Institution | Kyoto University (2016)
National Institute for Physiological Sciences (2015) |
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Principal Investigator |
OGAWA MASAAKI 京都大学, 医学研究科, 講師 (00716186)
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| Co-Investigator(Kenkyū-buntansha) |
真下 知士 大阪大学, 医学系研究科, 准教授 (80397554)
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| Research Collaborator |
ISHINO Seiya 京都大学, 医学研究科, 研究員
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 光遺伝学 / 遺伝子改変ラット / 連合学習 |
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| Outline of Final Research Achievements |
Many cognitive neuroscience studies have been examined neural correlates of cognitive functions. However, little is known about how those neural activities are dynamically generated by multiple inputs originating from other regions. To examine this, we have proposed to use one of prefrontal regions called orbitofrontal cortex (OFC) in rats that has been shown to be critical for cognitive function based on stimulus-outcome relationships as a model system. We have developed basic technologies to elucidate how activities of other regions that have direct inputs to OFC contribute to the generation of dynamic activity of OFC neurons.
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