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Measurements of chronically accumulated cortisol by using fingernail samples

Research Project

Project/Area Number 15K13169
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Experimental psychology
Research InstitutionNational Institute of Occupational Safety and Health,Japan

Principal Investigator

Izawa Shuhei  独立行政法人労働者健康安全機構労働安全衛生総合研究所, 産業ストレス研究グループ, 上席研究員 (00409757)

Co-Investigator(Kenkyū-buntansha) 野村 収作  長岡技術科学大学, 工学研究科, 准教授 (80362911)
三木 圭一  独立行政法人労働者健康安全機構労働安全衛生総合研究所, 研究推進・国際センター, 上席研究員 (90392894)
Research Collaborator Ogawa Namiko  文教大学, 生活科学研究所, 客員研究員 (60795524)
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywordsコルチゾール / 爪 / ストレス
Outline of Final Research Achievements

It is well known that chronic psychosocial stress could cause depression and heart disease. Considering the assessment of chronic psychosocial stress, in this study, we focused cortisol contained in fingernail samples, and investigated the procedure for determining fingernail cortisol. Fourteen healthy males provided fingernail sample, and we measured cortisol levels in the fingernails, in which we investigated the effects of ground-fingernail grain size and cortisol extraction time. The results indicated that finer grading and longer extraction time was associated with higher cortisol levels. This study demonstrated that the grain-size of ground fingernails and extraction time could affect the amount of extracted cortisol obtained from fingernails and should therefore be considered during fingernail cortisol assay.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 1 results,  Acknowledgement Compliant: 1 results) Presentation (5 results)

  • [Journal Article] 爪に含まれるコルチゾールの定量手法の検討―粉砕粒度と抽出時間の検討―2017

    • Author(s)
      井澤修平・吉田怜楠・大平雅子・山口歩・野村収作
    • Journal Title

      生理心理学と精神生理学

      Volume: 印刷中

    • NAID

      130007496259

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] 毛髪・爪試料を利用した慢性的・蓄積的なストレスホルモン分泌の評価:産業ストレス研究における展望2017

    • Author(s)
      井澤修平・三木圭一
    • Journal Title

      産業ストレス研究

      Volume: 24 Pages: 213-218

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Presentation] 毛髪・爪に含まれるストレス・ホルモンの定量手法の検討2016

    • Author(s)
      吉田怜楠・山口歩・大平雅子・井澤修平・野村収作
    • Organizer
      第32回日本ストレス学会学術総会
    • Place of Presentation
      東京
    • Year and Date
      2016-10-29
    • Related Report
      2016 Annual Research Report
  • [Presentation] 毛髪に含まれるコルチゾールの定量分析条件の検討2016

    • Author(s)
      大平雅子・吉田怜楠・山口歩・井澤修平・野村収作
    • Organizer
      日本生理人類学会第73回大会
    • Place of Presentation
      大阪
    • Year and Date
      2016-06-04
    • Related Report
      2016 Annual Research Report
  • [Presentation] 爪に含まれるコルチゾールの定量分析―抽出時間の検討―2016

    • Author(s)
      小川奈美子・井澤修平
    • Organizer
      第34回日本生理心理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2016-05-14
    • Related Report
      2016 Annual Research Report
  • [Presentation] 爪に含まれるコルチゾールの定量分析条件の検討2016

    • Author(s)
      大平雅子・吉田怜楠・山口歩・井澤修平・野村収作
    • Organizer
      第86回日本衛生学会学術総会
    • Place of Presentation
      旭川
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report 2015 Research-status Report
  • [Presentation] 爪に含まれるストレス・ホルモンの抽出手法の検証2016

    • Author(s)
      吉田怜楠・山口歩・大平雅子・井澤修平・野村収作
    • Organizer
      第11回日本感性工学会春季大会
    • Place of Presentation
      神戸
    • Year and Date
      2016-03-27
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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