| Project/Area Number |
15K13312
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Nanobioscience
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| Research Institution | The University of Tokyo |
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Principal Investigator |
SUYAMA Akira 東京大学, 大学院総合文化研究科, 教授 (90163063)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | DNAデバイス / ナノテクノロジー / 自己会合 / 3Dプリンター / 積層造形法 / 自己集合 / 積層造形 / DNAナノ構造体 / ３Dプリンター |
|---|
| Outline of Final Research Achievements |
DNA nanostructures are supramolecular structures made by self-assembly of DNA single-strands. They are expected to be used in fields such as material science, life science, medicine and so on. One of the causes that make it difficult to build large three-dimensional DNA nanostructures is the L-cubed problem. This problem can be solved by using the layered modeling method, which is the principle of a three-dimensional printer. In this study, we developed a nano-scale layered modeling method for constructing three-dimensional DNA nanostructures. By introducing two ports, to which the adapters with complementary DNA sequences bind specifically, into the structure of the DXAB tile forming a large two-dimensional array, we succeeded in developing DNA inks that satisfy the properties required for the nano-scale layered modeling method.
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