• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Restoration and functional recovery of brain neurons by using of atmospheric pressure plasma and cell stimulation generation device

Research Project

Project/Area Number 15K13392
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Plasma electronics
Research InstitutionTokyo City University

Principal Investigator

Hirata Takamichi  東京都市大学, 工学部, 教授 (80260420)

Co-Investigator(Kenkyū-buntansha) 高宮 真  東京大学, 大規模集積システム設計教育研究センター, 准教授 (20419261)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords化学修飾CNT / 立体ナノ構造 / 細胞刺激発生装置 / 脳神経細胞再生 / 大気圧プラズマ / 化学修飾CNT / 立体ナノ構造構 / 脳神経細胞再 / 大気圧プラズマ源 / 立体ナノ構造構築
Outline of Final Research Achievements

We did the basic experiment concerning the cardiomyocyte culture on CNT that modified the chemistry by the Plasma-Activation (PA) method for the construction of the solid nano structure to use Carbon nanotubes (CNT). We confirmed the cardiomyocyte was able to be cultured also on CNT as a result of the observation of the cardiomyocyte with the microscope. In addition, We made the wireless type electricity stimulation device for the living body burial for trial purposes. This device builds the electric power transmission circuit by the magnetic field resonance method to use two coils as a resonator into, and can generate the stimulation by electricity of a constant frequency. There was a problem of the size in small animals as a result of experimenting the burial with this device and a mock device of the same scale. It turned out that there was no problem in an middle animal.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (10 results)

All 2017 2016 Other

All Presentation (7 results) (of which Int'l Joint Research: 5 results,  Invited: 2 results) Book (1 results) Remarks (2 results)

  • [Presentation] Biocompatibility Evaluation with Amino Group-Modified Carbon Nanotube Films and Rats2017

    • Author(s)
      Y. Oki, S. Tsurubayashi, T. Yoshikawa, Kobayashi, and T. Hirata
    • Organizer
      TOIN International Symposium on Biomedical Engineering (BME 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Investigation of Relationship between Healing Effect by Plasma Irradiation and NO Concentration2017

    • Author(s)
      T. Yoshikawa, Y. Oki, S. Tsurubayashi, C. Kobayashi, and T. Hirata
    • Organizer
      TOIN International Symposium on Biomedical Engineering (BME 2017)
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Promotion of Angiogenesis Using Atmospheric Pressure Plasma Derived FGF-2/VEGF2017

    • Author(s)
      C. Kobayashi, T. Yoshikawa, A. Mori, and T. Hirata
    • Organizer
      The 70th Annual Gaseous Electronics Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Healing Mechanism Clarification of Plasma Irradiated Wound by Quantification and Detection of Superoxide Dismutase (SOD) Activity2017

    • Author(s)
      R. Tanaka, S. Shigekuni, S. Matsuda, T. Tamura, C. Kobayashi, A. Mori, and T. Hirata
    • Organizer
      The 70th Annual Gaseous Electronics Conference
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] プラズマ照射による火傷部位の治癒メカニズム解明を目的とした酸化ストレス測定2017

    • Author(s)
      田中莉沙子, 松田清香, 重國聖羅, 小林千尋, 森晃, 平田孝道
    • Organizer
      生体医工学シンポジウム2017 (JBMES2017)
    • Related Report
      2017 Annual Research Report
  • [Presentation] Emergency & Critical Care Medicine by Irradiation / Inhalation of Atmospheric Pressure Plasma2016

    • Author(s)
      T. Hirata, C. Tsutsui, A. Mori, T. Kanai, Y. Kudo, T. Izawa, M. Iwashita
    • Organizer
      The 13th Asia-Pacific Conference on Plasma Science and Technology (APCPST2016)
    • Place of Presentation
      Shanghai / China
    • Year and Date
      2016-05-19
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 大気圧プラズマの照射・吸入による疾患治療2016

    • Author(s)
      平田孝道
    • Organizer
      独)日本学術振興会プラズマ材料科学第153委員会 プラズマ材料科学
    • Place of Presentation
      弘済会館(東京都)
    • Year and Date
      2016-02-08
    • Related Report
      2015 Research-status Report
    • Invited
  • [Book] 機械の研究 第68巻、第3号(3月号)2016

    • Author(s)
      清水鉄司、平田孝道
    • Total Pages
      6
    • Publisher
      養賢堂(東京都)
    • Related Report
      2015 Research-status Report
  • [Remarks] 東京都市大学 工学部 医用工学科ホームページ

    • URL

      http://www.bme.tcu.ac.jp

    • Related Report
      2017 Annual Research Report 2016 Research-status Report 2015 Research-status Report
  • [Remarks] プラズマ再生医療合同チーム

    • URL

      http://www.bme.tcu.ac.jp/rmct/index.html

    • Related Report
      2017 Annual Research Report 2016 Research-status Report 2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi