| Project/Area Number |
15K13555
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Biological physics/Chemical physics/Soft matter physics
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| Research Institution | Tokyo University of Science |
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Principal Investigator |
Furue Hirokazu 東京理科大学, 基礎工学部材料工学科, 教授 (70289304)
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| Project Period (FY) |
2015-04-01 – 2019-03-31
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| Project Status |
Completed (Fiscal Year 2018)
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| Budget Amount *help |
¥3,250,000 (Direct Cost: ¥2,500,000、Indirect Cost: ¥750,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Keywords | 液晶 / 生物 / DNA / リオトロピック / ブルー相 / 円二色性 / イオン / 塩基 / 偏光顕微鏡 / 電気光学効果 / 両親媒性 / 円偏光二色性 / イオン密度 |
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| Outline of Final Research Achievements |
In this research, we focused on the close relationship between "organism" and "liquid crystal" and investigated the effect of adding DNA to liquid crystal as a biomolecule and the blue phase liquid crystal having a biosimilar structure. As liquid crystal materials, oil-based and water-based liquid crystals were produced. When considering the effect of adding DNA to liquid crystals of oil and water systems, it was found that DNA molecules generally have a strong effect on aqueous liquid crystals close to living bodies. As for the blue phase liquid crystal, the blue phase was successfully developed using a photopolymerizable monomer, and uniform alignment by alignment treatment, and a high mechanical strength sample based thereon were obtained.
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| Academic Significance and Societal Importance of the Research Achievements |
「生物」と「液晶」は同一の特徴を有し、密接な関係にあると考えられるが、具体的には未知の部分ばかりである。本研究では、生体分子としてDNAに着目したが、不均一な相互作用を液晶に導入し、液晶場におけるDNA分子の静的・動的な振る舞いを調査した。DNAの塩基種や塩基数、濃度によって液晶場の振る舞いが異なる結果も得られた。本研究の成果は、液晶を用いたバイオセンサー等に繋がるものと期待される。また、ブルー相液晶を用いた研究では、生物で観られるような高次構造・高機能性を有する材料を、液晶を用いて自己組織的に低エネルギーで実現する手法を提案した。
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