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Synthesis of boron-containing organic materials by novel nucleophilic borylation

Research Project

Project/Area Number 15K13633
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Organic chemistry
Research InstitutionHokkaido University

Principal Investigator

ITO Hajime  北海道大学, 工学研究院, 教授 (90282300)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywordsシリルボラン / ホウ素化 / ケイ素化 / ホウ素化反応 / 電子材料 / 光物性
Outline of Final Research Achievements

Organoboron compounds are vital synthetic intermediates for many organic transformations such as Suzuki coupling. Organoboron compounds are also important for organic materials. The researcher previously developed silyl boron/base reaction system for their efficient synthesis. In this research, the reaction has been expanded by the mechanistic insight obtained by calculation studies. New synthetic procedures for hetero-aromatic organoboron compounds, functionalized organoboron compounds, triaryl boron compounds have been developed.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (11 results)

All 2017 2016 2015 Other

All Journal Article (4 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Acknowledgement Compliant: 2 results) Presentation (6 results) (of which Int'l Joint Research: 5 results,  Invited: 6 results) Remarks (1 results)

  • [Journal Article] Transition-Metal-Free Boryl Substitution using Silylboranes and Alkoxy Bases2017

    • Author(s)
      Yamamoto, E.; Maeda, S.; Taketsugu, T.; Ito, H.
    • Journal Title

      Yamamoto, E.; Maeda, S.; Taketsugu, T.; Ito, H.

      Volume: 印刷中

    • NAID

      120006484242

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Transition-metal-free B-B and B-interelement reactions with organic molecules2017

    • Author(s)
      Cuenca, A. B.; Shishido, R.; Ito, H.; Fernandez, E.
    • Journal Title

      Chemical Society Reviews

      Volume: 46 Issue: 2 Pages: 415-430

    • DOI

      10.1039/c6cs00692b

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Direct Introduction of a Dimesitylboryl Group Using Base-Mediated Substitution of Aryl Halides with Silyldimesitylborane2016

    • Author(s)
      Yamamoto, E; Izumi, K.; Shishido, R.; Seki, T.; Tokodai, N.; Ito, H.
    • Journal Title

      Chem. Eur. J.

      Volume: 22 Issue: 49 Pages: 17547-17551

    • DOI

      10.1002/chem.201604021

    • NAID

      120006366477

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Boryl substitution of functionalized aryl-, heteroaryl-, and alkenyl halides with silylborane and alkoxy base: expanded scope and mechanistic studies2015

    • Author(s)
      Eiji Yamamoto, Satoshi Ukigai, Hajime Ito
    • Journal Title

      Chemical Science

      Volume: 6 Issue: 5 Pages: 2943-2951

    • DOI

      10.1039/c5sc00384a

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] Copper-catalyzed borylations: from the beginning to our recent study2017

    • Author(s)
      伊藤肇
    • Organizer
      湖北工業大学講演会
    • Place of Presentation
      湖北工業大学、武漢市、中国
    • Year and Date
      2017-04-27
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Copper-catalyzed borylations: from the beginning to our recent study2017

    • Author(s)
      伊藤肇
    • Organizer
      中国科学院成都生物研究所講演会
    • Place of Presentation
      中国科学院成都生物研究所、成都市、中国
    • Year and Date
      2017-04-25
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Copper-Catalyzed Borylation: the Discovery and the Recent Progres2016

    • Author(s)
      伊藤 肇
    • Organizer
      第26回光学活性化合物シンポジウム
    • Place of Presentation
      日本薬学会館長井記念ホール、東京
    • Year and Date
      2016-11-25
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 銅(I)触媒による光学活性有機ホウ素化合物の新しい合成法2016

    • Author(s)
      伊藤肇
    • Organizer
      京都大学集中講義 特別講演会
    • Place of Presentation
      京都大学、京都
    • Year and Date
      2016-11-22
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Strange reactivity of silylborane: Boryl substitution of organic halides with silylborane/alkoxy base systems2015

    • Author(s)
      Hajime Ito
    • Organizer
      IUPAC Symposium
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2015-08-09
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Copper-Catalyzed and Base-Promoted Borylations2015

    • Author(s)
      Hajime Ito
    • Organizer
      Stockholm University Lecture
    • Place of Presentation
      Stockholm University, Stockholm, Sweden
    • Year and Date
      2015-06-09
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Remarks]

    • URL

      http://labs.eng.hokudai.ac.jp/labo/organoelement/

    • Related Report
      2016 Annual Research Report

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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