Development of circular dichroism microscopy for structural analysis of chiral material
| Project/Area Number |
15K13708
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Polymer chemistry
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| Research Institution | Japan Atomic Energy Agency (2016)
Kyoto University (2015) |
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Principal Investigator |
Hiroyuki Aoki 国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 J－PARCセンター, 研究副主幹 (90343235)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 円偏光二色性 / 共焦点顕微鏡 / キラル |
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| Outline of Final Research Achievements |
The current project aims at the development of circular dichroism (CD) microscopy. In a microscopy measurement, the CD signal have to be detected from a small sample volume because the probe beam is focused. Modulated elliptical polarized light enables the highly sensitive CD measurement; however, the conventional method using a rotating retarder cannot increase the modulation rate faster than the oder of 1 Hz. In the current study, novel modulation optics has been developed by using a pair of electro-optics (EO) modulators. The EO modulators are inserted in the optical axis at angles of -4 and +4 degrees, and the high voltage is applied alternately to each EO modulator. This system enabled the modulation of the polarization state up to 10 kHz. Moreover, the polarization modulation system was integrated into a microscopy system, and nanometric polymer particle was observed successfully.
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Report
(3 results)
Research Products
(5 results)
