• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Development of circular dichroism microscopy for structural analysis of chiral material

Research Project

Project/Area Number 15K13708
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Polymer chemistry
Research InstitutionJapan Atomic Energy Agency (2016)
Kyoto University (2015)

Principal Investigator

Hiroyuki Aoki  国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 J-PARCセンター, 研究副主幹 (90343235)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords円偏光二色性 / 共焦点顕微鏡 / キラル
Outline of Final Research Achievements

The current project aims at the development of circular dichroism (CD) microscopy. In a microscopy measurement, the CD signal have to be detected from a small sample volume because the probe beam is focused. Modulated elliptical polarized light enables the highly sensitive CD measurement; however, the conventional method using a rotating retarder cannot increase the modulation rate faster than the oder of 1 Hz. In the current study, novel modulation optics has been developed by using a pair of electro-optics (EO) modulators. The EO modulators are inserted in the optical axis at angles of -4 and +4 degrees, and the high voltage is applied alternately to each EO modulator. This system enabled the modulation of the polarization state up to 10 kHz. Moreover, the polarization modulation system was integrated into a microscopy system, and nanometric polymer particle was observed successfully.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (5 results)

All 2016 2015

All Presentation (5 results) (of which Int'l Joint Research: 4 results,  Invited: 3 results)

  • [Presentation] Single-Molecule Analysis of Polymer Materials by Fluorescence Nanoscopy2016

    • Author(s)
      Hiroyuki Aoki
    • Organizer
      Nano S&T-2016
    • Place of Presentation
      Singapore
    • Year and Date
      2016-10-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Conformational analysis of single polymer chain in thin films by super-resolution fluorescence microscopy2016

    • Author(s)
      Hiroyuki Aoki
    • Organizer
      IUPAC-PSK 40
    • Place of Presentation
      Jeju, Korea
    • Year and Date
      2016-10-04
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Properties of Polymer Materials Studied by Super-resolution Optical Microscopy2016

    • Author(s)
      Hiroyuki Aoki
    • Organizer
      International Symposium of Spectroscopical Society of Japan 2016
    • Place of Presentation
      大阪大学豊中キャンパス(大阪府豊中市)
    • Year and Date
      2016-05-25
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Conformation of single polymer chain in spin-cast thin films revealed by super-resolution fluorescence microscopy2015

    • Author(s)
      Hiroyuki Aoki, Taiki Kuroda, Toru Asada, Tomomi Tanii
    • Organizer
      Pacifichem 2015
    • Place of Presentation
      Honolulu, HI, USA
    • Year and Date
      2015-12-15
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 超解像光学顕微鏡によるスピンコート薄膜中の高分子鎖のコンホメーション解析2015

    • Author(s)
      青木裕之, 谷井友海
    • Organizer
      2015年光化学討論会
    • Place of Presentation
      大阪市立大学(大阪府大阪市)
    • Year and Date
      2015-09-09
    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi