Development of micro-3D tissues having capillary vessel network
| Project/Area Number |
15K13719
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Analytical chemistry
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| Research Institution | Gunma University |
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Principal Investigator |
Sato Kiichi 群馬大学, 大学院理工学府, 准教授 (50321906)
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| Co-Investigator(Renkei-kenkyūsha) |
TSUNODA Kin-ichi 群馬大学, 大学院理工学府, 教授 (30175468)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | マイクロ流体デバイス / マイクロチップ / 血管模倣デバイス / 生体模倣デバイス / 動物実験代替法 / バイオアッセイ / 三次元培養 |
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| Outline of Final Research Achievements |
In this research, we developed 3D tissues of muscle and fat having capillary network inside and blood vessels built in a hydrogel to realize muscle, fat, and peripheral tissue models for drug delivery and distribution studies. By using commercially available human primary cells, micro-3D tissues having capillary vessel network inside were realized. The results of this work will be applicable to various fields including drug development and risk evaluation of toxic chemicals.
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Report
(3 results)
Research Products
(13 results)
