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Micro Chmical modification tool for region selective surface treatment

Research Project

Project/Area Number 15K13731
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Analytical chemistry
Research InstitutionTokyo Metropolitan University

Principal Investigator

Uchiyama Katsumi  首都大学東京, 都市環境科学研究科, 教授 (40151899)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Fiscal Year 2015: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Keywords微小化学反応描画ツール / ケミカルファブリケーション / 微小化学描画 / 微小化学反応 / 微細化学描画 / マイクロ流体 / マイクロ・ナノパターニング
Outline of Final Research Achievements

Various micro/nano surface-modification techniques such as photolithography, dip-pen lithography and micro-fluidic systems have been developed. And they were used to extend the functionalities of solid surfaces. While those approaches work in the “open space”, push&/pull systems which work in solutions have recently drawn considerable attention. While microscale, region-selective chemical reactions have remained unattainable. This work reports a micro-chemical pen that enables region-selective chemical reactions for the micro/nano surface modification. The chemical pen is based on the principle of microfluidic laminar flows. The micro scale diffusion layer performs as the working region of the surface modification. This work is the first demonstration of an open micro reactor. The characteristics of the micro chemical pen are confirmed by different types of reactions, including inorganic chemistry, polymer science, electrochemistry and biological sample treatment.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (14 results)

All 2017 2016 2015 Other

All Int'l Joint Research (1 results) Journal Article (5 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 5 results,  Acknowledgement Compliant: 1 results) Presentation (6 results) (of which Int'l Joint Research: 4 results,  Invited: 4 results) Remarks (2 results)

  • [Int'l Joint Research] Department of Chemistry/Tsinghua University(China)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Microchemical Pen: An Open Microreactor for Region-Selective Surface Modification2016

    • Author(s)
      S. Mao, C. Sato, Y. Suzuki, J. Yang, H. Zeng, H. Nakajima, M. Yang, J-M. Lin, K. Uhciyama
    • Journal Title

      ChemPhysChem

      Volume: 17 Issue: 20 Pages: 3155-3159

    • DOI

      10.1002/cphc.201600857

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] インクジェットによる超微小液滴生成とクロマトグラフィーへの応用2016

    • Author(s)
      内山一美
    • Journal Title

      分析化学

      Volume: 65 Pages: 1-11

    • NAID

      130005124375

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] マルチビームスプリッターを用いる二次元表面プラズモン共鳴センサーによる多成分同時イムノアッセイの検討2015

    • Author(s)
      森岡和大, 中嶋秀, 辺見彰秀, 飯田慎平, 北村 文, 曽 湖烈, 加藤俊吾, 内山一美
    • Journal Title

      分析化学

      Volume: 65 Pages: 79-85

    • NAID

      130005131107

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Quantitative on-line concentration for capillary electrophoresis with inkjet sample introduction technique2015

    • Author(s)
      Y. Rang, H. Zeng, H. Nakajima, S. Kato, K. Uchiyama
    • Journal Title

      Journal of separation Sciences

      Volume: 38 Pages: 2722-2728

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Investigation of monodisperse droplet generation in liquids by inkjet2015

    • Author(s)
      H. Zeng, J. Yang, D. Katagiri, Y. Rang, S. Xue, H. Nakajima, K. Uchiyama
    • Journal Title

      Sensors and Actuators B

      Volume: 220 Pages: 958-961

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Presentation] マイクロ化学ペンによるナノ・マイクロ化学構造外の作製2017

    • Author(s)
      内山一美
    • Organizer
      化学センサ研究会
    • Place of Presentation
      首都大学東京(東京都八王子市)
    • Year and Date
      2017-03-25
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] μ/nano-chemical pen and new digital PCR2017

    • Author(s)
      Katsumi Uchiyama
    • Organizer
      Colloquim on analytical chemistry
    • Place of Presentation
      Beijing (China)
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] マイクロ流体をベースとした化学ペン2016

    • Author(s)
      毛思鋒,佐藤知穂,鈴木雄馬,楊建民,曾湖烈,中嶋秀,楊明,林金明,内山一美
    • Organizer
      有機微量分析研究懇談会
    • Place of Presentation
      アイーナ(岩手県盛岡市)
    • Year and Date
      2016-05-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] Drop-by-drop chemical reaction and sample introduction for capillary electrophoresis2015

    • Author(s)
      Katsumi Uchiyama
    • Organizer
      The 16th Beijing conference and exhibition on instrumental analysis
    • Place of Presentation
      Beijin, China
    • Year and Date
      2015-10-28
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Quantitative on-line Concentration and Reaction for Capillary Electrophoresis with Inkjet Sample Introduction2015

    • Author(s)
      Y. Rang, F. Chen, H. Zeng, H. Nakajima, S. Kato, J-M. Lin, K. Uchiyama
    • Organizer
      2015 China-Japan=Korea Symposium on analytical Chemistry
    • Place of Presentation
      Busan, Korea
    • Year and Date
      2015-10-13
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Mirofluidic based chemical pen2015

    • Author(s)
      S. Mao, C. Sato, H. Zeng, H. Nakajima, K. Uchiyama
    • Organizer
      The 8th international forum on chemistry of functional organic chemicals
    • Place of Presentation
      Tokyo University
    • Year and Date
      2015-10-07
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 内山研究室

    • URL

      http://www.comp.tmu.ac.jp/uchiyama/

    • Related Report
      2016 Annual Research Report
  • [Remarks] 環境分析化学研究室(内山研究室)

    • URL

      http://www.comp.tmu.ac.jp/uchiyama/

    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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