| Project/Area Number |
15K13734
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Bio-related chemistry
|
|---|
| Research Institution | Tokushima Bunri University |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
梶本 真司 東北大学, 薬学研究科, 講師 (80463769)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
Yamada Ryo 大阪大学, 大学院基礎工学研究科, 准教授 (20343741)
|
|---|
| Research Collaborator |
Vladimír Sychrovský
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
|
|---|
| Keywords | 核酸関連化学 / 生物無機化学 / 生物構造化学 / 生体構造化学 |
|---|
| Outline of Final Research Achievements |
We have determined three-dimensional structure of a metallo-DNA with uninterrupted one-dimensional (1D) metal-array. In this crystal structure, the DNA duplexes containing a 1D metal-array further formed a pseudo-continuous duplex according to the crystal symmetry. This means that 1D metal-array is continuously formed from one edge of the crystal to another edge. We succeeded in creating a 1D metal-array of a visible length. It should be also mentioned that none could obtain such a long metallo-DNA until now, although many researchers have made a lot of trials all over the world. From now on, using this crystal, we were able to examine electrical properties like a conductivity of a 1D metal-array in the long metallo-DNA. In conclusion, we were able to report truly long molecular nanowire made of metallo-DNA molecule, for the first time.
|
