Generation of long metallo-DNA nanowire: Toward a conductive molecular wire
| Project/Area Number |
15K13734
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Bio-related chemistry
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| Research Institution | Tokushima Bunri University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
梶本 真司 東北大学, 薬学研究科, 講師 (80463769)
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| Co-Investigator(Renkei-kenkyūsha) |
Yamada Ryo 大阪大学, 大学院基礎工学研究科, 准教授 (20343741)
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| Research Collaborator |
Vladimír Sychrovský
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
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| Keywords | 核酸関連化学 / 生物無機化学 / 生物構造化学 / 生体構造化学 |
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| Outline of Final Research Achievements |
We have determined three-dimensional structure of a metallo-DNA with uninterrupted one-dimensional (1D) metal-array. In this crystal structure, the DNA duplexes containing a 1D metal-array further formed a pseudo-continuous duplex according to the crystal symmetry. This means that 1D metal-array is continuously formed from one edge of the crystal to another edge. We succeeded in creating a 1D metal-array of a visible length. It should be also mentioned that none could obtain such a long metallo-DNA until now, although many researchers have made a lot of trials all over the world. From now on, using this crystal, we were able to examine electrical properties like a conductivity of a 1D metal-array in the long metallo-DNA. In conclusion, we were able to report truly long molecular nanowire made of metallo-DNA molecule, for the first time.
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Report
(4 results)
Research Products
(22 results)
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[Journal Article] The Structure Determination of AgI-mediated Cytosine-Cytosine Base Pair within DNA Duplex in Solution with 1H/15N/109Ag NMR Spectroscopy.2016
Author(s)
Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Sebera, Katsuyuki Nakashima, Jiro Kondo, Daichi Yamanaka, Yoshinori Kondo, Itaru Okamoto, Akira Ono, Vladimir Sychrovsky, Chojiro Kojima, and Yoshiyuki Tanaka
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Journal Title
Chemistry - A European Journal
Volume: 22
Pages: 13028-13031
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Direct detection of the mercury-nitrogen bond in the thymine-HgII-thymine base-pair with 199Hg NMR spectroscopy2015
Author(s)
Takenori Dairaku, Kyoko Furuita, Hajime Sato, Jakub Sebera, Daichi Yamanaka, Hiroyuki Otaki, Shoko Kikkawa, Yoshinori Kondo, Ritsuko Katahira, F. Matthias Bickelhaupt, Celia Fonseca Guerra, Akira Ono, Vladimir Sychrovsky, Chojiro Kojima and Yoshiyuki Tanaka
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Journal Title
Chem. Commun.
Volume: 51
Pages: 8488-8491
DOI
Related Report
Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
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[Journal Article] Structures, Physicochemical Properties, and Applications of T-Hg(II)-T, C-Ag(I)-C, and Other Metallo-Base-Pairs2015
Author(s)
Yoshiyuki Tanaka, Jiro Kondo, Vladimir Sychrovsky, Jakub Sebera, Takenori Dairaku, Hisao Saneyoshi, Hidehito Urata, Hidetaka Torigoe and Akira Ono
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Journal Title
Chem. Comm.
Volume: 51
Pages: 17313-17360
DOI
Related Report
Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
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