| Project/Area Number |
15K13758
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Green/Environmental chemistry
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| Research Institution | Kobe University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
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| Keywords | パラジウム触媒 / 酸化反応 / フェノール / レゾルシノール / レスベラトロール / パラジウム / Pd/C / エチレン |
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| Outline of Final Research Achievements |
The conversion of cyclohexanone and substituted cyclohexanones to alkyl aryl ethers using a PdC-ethylene system is discussed, where ethylene functions as a hydrogen acceptor. The obtained ethers are easily transformed into the corresponding phenols by treatment with BBr3. Direct conversion of cyclohexenone to phenol in the presence of a catalytic amount of PdC under an ethylene atmosphere.
The conversion of substituted 1,3-cyclohexanediones to the alkyl ethers of resorcinol using a PdC-ethylene system is reported. In these reactions, ethylene works as a hydrogen acceptor. The efficient synthesis of resveratrol was achieved using this protocol as a key step. In addition, the direct formation of substituted resorcinols was carried out by adding K2CO3 into the reaction media.
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