| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Outline of Final Research Achievements |
The diffusion coefficients of biological molecules, such as proteins, reflect their size, molecular structure, conformational changes, and inter-molecular interactions. Therefore, how the diffusion coefficient of biological samples changes in liquid solution is essential knowledge for clinical diagnosis and drug discovery. In this study, novel techniques such as (1) the simple fabrication technique of hydrogenated amorphous silicon, (2) the optical sorting technique for the high sensitive measurement, and (3) the new channel structure applicable for the biological sample, have been developed.
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