Development of fluorination catalysts generating metal oxo species as active species
| Project/Area Number |
15K14226
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Catalyst/Resource chemical process
|
|---|
| Research Institution | Doshisha University |
|---|
Principal Investigator |
Hitomi Yutaka 同志社大学, 理工学部, 教授 (20335186)
|
|---|
| Project Period (FY) |
2015-04-01 – 2018-03-31
|
| Project Status |
Completed (Fiscal Year 2017)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2016: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
|
|---|
| Keywords | 鉄錯体 / 触媒 / フッ素化 / オキソ種 / 酸化剤 / C-H活性化 / アルカン / 酵素 / 錯体 / 酸化 / マンガン錯体 |
|---|
| Outline of Final Research Achievements |
Inspired by the reaction mechanism of mononuclear nonheme iron enzyme, SyrB2, which catalyzes direct halogenation of alkane C-H bonds under mild conditions, novel fluorination catalysts have been designed. SyrB2 generates nonheme oxoiron(IV) species as an active oxidant, which has a halogen ligand coordinated cis to the oxygen ligand. In order to reproduce the biological oxidant, new iron complexes that contain two cis-labile coordination sites have been synthesized. Some fluorinated products have been obtained using the catalysts under mild conditions.
|
Report
(4 results)
Research Products
(40 results)
