| Budget Amount *help |
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2017: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Outline of Final Research Achievements |
In this proposal, to develop the novel catalyst for carbon dioxide conversion to methanol, formate, aldehyde and alcohol dehydrogenase hybrid biocatalysts system is designed. The interaction with alcohol dehydrogenase catalyzing the formaldehyde-methanol conversion and single-electron reduced methylviologen was investigated using enzymatic kinetic analysis. The interaction with aldehyde dehydrogenase catalyzing the formic acid-formaldehyde conversion and single-electron reduced methylviologen also was investigated using enzymatic kinetic analysis. As a result of enzymatic kinetic analysis, the interaction with aldehyde dehydrogenase shows stronger affinity for single-electron reduced methylviologen than other dehydrogenases. Based on these results, carbon dioxide-methanol conversion by formate, aldehyde, alcohol dehydrogenases system with single-electron reduced methylviologen was achieved.
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