| Project/Area Number |
15K14345
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Neurochemistry/Neuropharmacology
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| Research Institution | Nagoya University (2016)
The University of Tokyo (2015) |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 分界条床核 / カルシウム依存的リン酸化酵素 / 扁桃体中心核 / 情動 / 局所回路 / 恐怖記憶 / 脳神経科学 / 不安 |
|---|
| Outline of Final Research Achievements |
The occurrence of anxiety is modified by environment. One of the subcortical nucleus related to anxiety regulation is the bed nucleus of stria terminalis and the central nucleus of amygdala, which are included in the extended amygdala. In this study we focused on specific groups of neurons in these regions. We performed anatomical study to reveal connections between two regions. Furthermore, we established methods measuring and manipulating the neuronal groups in this area to understand the pathophysiology of anxiety disorders.
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