| Project/Area Number |
15K14485
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Biophysics
|
|---|
| Research Institution | Osaka University (2016)
Kyoto University (2015) |
|---|
Principal Investigator |
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 1分子計測・操作 / ナノマシン / 蛋白質 / 核酸 / 1分子計測(SMD) / 分子機械 / マイクロ・ナノデバイス |
|---|
| Outline of Final Research Achievements |
Toward the handheld device, downsizing the subcomponent system is the key. Here,we made an orthogonal self-contained device by integrating an enzyme, T7 RNA polymerase, and multiple target gene substrates onto a DNA origami-based nano-chip.Our nano-chip allowed us to rationally design the gene expression at single chip level, suggesting that the integrated approach may provide a basis for gene expression system of handheld devices.
|
