| Project/Area Number |
15K14504
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Multi-year Fund |
|---|
| Research Field |
Cell biology
|
|---|
| Research Institution | Ochanomizu University |
|---|
Principal Investigator |
Kishimoto Takeo お茶の水女子大学, サイエンス&エデュケーションセンター, 客員教授 (00124222)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
奥村 英一 東京工業大学, 生命理工学院, 助教 (00323808)
|
|---|
| Project Period (FY) |
2015-04-01 – 2017-03-31
|
| Project Status |
Completed (Fiscal Year 2016)
|
| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 卵成熟 / ホルモン受容体 / ヒトデ卵 |
|---|
| Outline of Final Research Achievements |
Oocyte maturation is a prerequisite for embryonic deveoplment after fertilization, whereas a putative oocyte surface receptor of maturation-inducing hormone has long been a major missing link. Here, we intended to identify the surface receptor in starfish oocytes through isolation of maturation-inducing hormone-binding protein. At present, we isolated and identified the protein complex that binds to starfish maturation-inducing hormone. However, it remains unclear whether the complex is actually involved in hormonal signaling that leads to oocyte maturation.
|
