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Evaluation of Brown Adipose Tissue Activity

Research Project

Project/Area Number 15K14616
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied anthropology
Research InstitutionKyushu University

Principal Investigator

Maeda Takafumi  九州大学, 芸術工学研究院, 教授 (90301407)

Co-Investigator(Kenkyū-buntansha) 米代 武司  カリフォルニア大学サンフランシスコ校, 糖尿病センター, 学振海外特別研究員 (40724167)
松下 真美  天使大学, 看護栄養学部, 助教 (60517316)
斉藤 昌之  北海道大学, 獣医学研究院, 名誉教授 (80036441)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥4,030,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥930,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords環境適応能 / 寒冷適応 / 機能的潜在性 / 生理人類学 / 褐色脂肪 / 寒冷誘発熱産生
Outline of Final Research Achievements

The purpose of this study was to examine the validity of supraclavicular subcutaneous tissue temperature as an index of brown adipose tissue activity. We measured the brown adipose tissue activity in winter by FDG-PET/CT method. We also performed cold exposure test and measured metabolic rate, rectal and skin temperatures, blood flow, and subcutaneous tissue temperatures at supraclavicular and breast during cold exposure for 90 min in summer and winter. As a result, the SUVmax, which was an index of brown adipose activity, was not related with supraclavicular skin temperature but related with the supraclavicular subcutaneous tissue temperature. Also the supraclavicular subcutaneous tissue temperature maintained during cold exposure in winter, but that was decreasing in summer. These results suggested that the brown adipose tissue activity was evaluated by the supraclavicular subcutaneous tissue temperature.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (5 results)

All 2018 2017 2016 2015

All Presentation (5 results) (of which Int'l Joint Research: 1 results,  Invited: 3 results)

  • [Presentation] 寒冷環境への適応2018

    • Author(s)
      前田享史
    • Organizer
      応用生理人類学研究センターシンポジウム「現代人の環境適応能 ~生理人類学の視点から~」
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Effects of seasonal change in basal metabolic rate on the seasonal difference in cold-induced thermogenesis.2017

    • Author(s)
      Takafumi Maeda
    • Organizer
      The 13th International Congress of Physiological Anthropology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] ヒトの耐寒性とその影響要因2016

    • Author(s)
      前田 享史
    • Organizer
      人類学若手の会第4回総合研究集会
    • Place of Presentation
      九州大学大橋キャンパス3号館
    • Year and Date
      2016-02-06
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Cold Adaptability in Human, Immune Function and Environmental Condition, Thermal Stimuli and Mental Task Performance2016

    • Author(s)
      Maeda Takafumi
    • Organizer
      Research Seminar of NUTRIM School of Nutrition and Translational Research in Metabolism in Maastricht University
    • Place of Presentation
      Maastricht University, The Netherland
    • Year and Date
      2016-01-19
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 鎖骨上窩皮下組織温から見た褐色脂肪活性2015

    • Author(s)
      小林功嗣,前田享史,米代武司,松下真美,斉藤昌之
    • Organizer
      第23回 衛生工学シンポジウム
    • Place of Presentation
      北海道大学工学部 フロンティア応用科学研究棟
    • Year and Date
      2015-11-12
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2022-04-04  

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