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The relationship between a gene associated with sweat gland and sweating function in humans

Research Project

Project/Area Number 15K14618
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Applied anthropology
Research InstitutionKobe University

Principal Investigator

Kondo Narihiko  神戸大学, 人間発達環境学研究科, 教授 (70215458)

Co-Investigator(Kenkyū-buntansha) 井上 芳光  大阪国際大学, 人間科学部, 教授 (70144566)
前田 享史  九州大学, 芸術工学研究院, 教授 (90301407)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords発汗機能 / 遺伝子 / ヒト / 遺伝
Outline of Final Research Achievements

To investigate a relationship between sweating function and EDAR370A gene associated with activated sweat gland in humans, we compared activated sweat gland and sweat function in a subject with EDAR370A with a subject without this gene. We recruited 40 healthy subjects (age range of 20-80 years old). We found only 4 subjects with EDAR370A. Although number of activated sweat glands in the subjects with EDAR370A gene tended to be greater than that in the subjects without this gene, sweat function was not markedly different between the groups. However, we could not conclude the effect of EDAR370A on human sweat function because sample size of subjects without EDAR370A was extremely small.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (8 results)

All 2017 2016 2015

All Journal Article (2 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 1 results,  Acknowledgement Compliant: 1 results) Presentation (6 results) (of which Int'l Joint Research: 5 results,  Invited: 6 results)

  • [Journal Article] 運動時におけるヒトの発汗調節特性2017

    • Author(s)
      近藤徳彦,天野達郎,Nicola Gerrett
    • Journal Title

      発汗学

      Volume: 24 Pages: 2-5

    • Related Report
      2016 Research-status Report
  • [Journal Article] Maximum rate of sweat ions reabsorption during exercise with regional differences, sex, and exercise training.2017

    • Author(s)
      Amano T, Hirose M, Konishi K, Gerrett N, Ueda H, Kondo N, Inoue Y
    • Journal Title

      Eur J Appl Physiol

      Volume: 117 Issue: 7 Pages: 1317-1327

    • DOI

      10.1007/s00421-017-3619-8

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Presentation] Characteristics of sweating response in habitually trained individuals and its potential mechanisms2017

    • Author(s)
      Amano T, Kondo N
    • Organizer
      The 17th International Conference on Environmental Ergonomics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] Sweat glands ion reabsorption2017

    • Author(s)
      Gerrett N, Amano T, Kondo N
    • Organizer
      The 17th International Conference on Environmental Ergonomics
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research / Invited
  • [Presentation] 運動時におけるヒトの発汗調節特性2016

    • Author(s)
      近藤徳彦,天野達郎,Nicola Gerrett
    • Organizer
      第24回日本発汗学会総会
    • Place of Presentation
      大阪大学医学系研究科(大阪府・吹田市)
    • Year and Date
      2016-08-27
    • Related Report
      2016 Research-status Report
    • Invited
  • [Presentation] Thermoregulation in the tropics2015

    • Author(s)
      Kondo N, Amano T, Inoue Y, Nishiyasu
    • Organizer
      The 8th the Asian and Oceanian Physiological Societies (FAOPS) Congress
    • Place of Presentation
      Banckok, Thaihland
    • Year and Date
      2015-11-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Integrated control of heat loss responses during exercise in humans2015

    • Author(s)
      Kondo N, Amano T, Inoue Y, Nishiyasu T
    • Organizer
      International Conference on Movement, Health & Exercise 2015
    • Place of Presentation
      Penang, Malaysia
    • Year and Date
      2015-10-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Changes in heat loss responses with exercise training2015

    • Author(s)
      Kondo N, Amano T, Inoue Y, Nishiyasu T
    • Organizer
      International Conference on Movement, Health & Exercise 2015
    • Place of Presentation
      Penang, Malaysia
    • Year and Date
      2015-10-05
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited

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Published: 2015-04-16   Modified: 2019-03-29  

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