Establishment of early pregnancy diagnosis using circulating exosomal microRNA in cows
| Project/Area Number |
15K14838
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Animal production science
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| Research Institution | Iwate University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
TAKAHASHI Toru 岩手大学, 農学部, 教授 (20355738)
WATANABE Daisaku 北里大学, 獣医学部, 教授 (10406895)
IGA Kosuke 独立行政法人農業・食品産業技術総合研究機構, 東北農業研究センター, 主任研究員 (00343963)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | マイクロRNA / miRNA |
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| Outline of Final Research Achievements |
In the present study, we investigated the possibility of pregnancy diagnosis in cows using exosomal microRNA (miRNA) as a new biomarker. The present results demonstrated that some miRNAs were highly contained in pregnant plasma compared with non-pregnant. Furthermore, we identified also the reference miRNA for quantification of miRNA in plasma. These results indicate that measurement of selected miRNAs are reliable indicators of pregnancy in cows.
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Report
(4 results)
Research Products
(6 results)
