| Project/Area Number |
15K14855
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | Yamaguchi University |
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Principal Investigator |
Sato Koichi 山口大学, 共同獣医学部, 教授 (90205914)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 消化管上皮細胞 / 筋線維芽細胞 / 3次元培養 / 薬物透過吸収 |
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| Outline of Final Research Achievements |
As for the medical supplies and the effect and the safety of functional foods done ingestion of, the result of the digestive organs transmission absorption examination that I used a cultured cell for becomes important materials in evaluation to depend on the absorption from digestive organs. However, single-layered culture system by single epithelium cell is used for the current absorption transmission examination system. That a cortex consisting of various epithelium cells in the digestive organs of the living body and myofibroblast cell arrange it right under an epithelium cell are not considered.
I this project, I establish the material transmission absorption examination system that is almost living body environment. And I offer the new evaluation method how medicine and the effectiveness and the safety of functional foods were reflected more.
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