Studies on autoimmune responses in molecular pathology of canine demodicosis
| Project/Area Number |
15K14869
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Veterinary medical science
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| Research Institution | Gifu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
谷 健二 山口大学, 共同獣医学部, 准教授 (00365420)
西藤 公司 東京農工大学, (連合)農学研究科(研究院), 准教授 (20365422)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,900,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥900,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥2,080,000 (Direct Cost: ¥1,600,000、Indirect Cost: ¥480,000)
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| Keywords | 犬毛包虫症 / 自己免疫疾患 |
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| Outline of Final Research Achievements |
The skin sample obtained from a dog that had suffered canine demodicosis were successfully transplanted in three NOD-SCID mice. CD8+ lymphocytes collected from three dogs (a dog which skin had been collected, a dog with canine demodicosis, a healthy dog) were then transferred to the mice. The lymphocyte transfer did not induce any clinical signs. Forty two days after the lymphocyte transfer, a dermatopathological examination was performed and indicated no inflammation in epidermis, dermis and follicles. These were no significant difference on pathological findings among three different mice.
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Report
(3 results)
Research Products
(1 results)
