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Quality improvement of medicinal plants using insect-plant interaction

Research Project

Project/Area Number 15K14972
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Natural medicines
Research InstitutionRitsumeikan University

Principal Investigator

Tanaka Ken  立命館大学, 薬学部, 教授 (60418689)

Research Collaborator TAKABAYASI Junji  
TAMURA Takayuki  
TATSUO Yoshiaki  
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Keywords化学生態学 / 生薬成分 / 植物昆虫相互作用
Outline of Final Research Achievements

Medicinal plants produce many compounds to help them survive in severe environments. The pharmaceutical properties of many crude drugs are attributable to such secondary metabolites. Therefore, knowledge of the actual function of secondary metabolites triggered in response to environmental factors could be utilized to produce highly functional crude drugs. The present study aims at investigating the prompt response of short period damaged Angelica acutiloba utilizing metabolomic and proteomic analyses. In addition, LC-MS analyses of the larval oral regurgitation of Papilio machaon were performed to identify the natural elicitor.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2018 2017 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (4 results)

  • [Journal Article] Oviposition inhibitor in Umbelliferous medicinal plants for the common yellow swallowtail (Papilio machaon)2018

    • Author(s)
      Morino C., Morita Y., Minami K., Nishidono Y., Nakashima Y., Ozawa R., Takabayashi J., Ono N., Kanaya S., Tamura T., Tezuka Y., Tanaka K.
    • Journal Title

      Journal of Natural Medicines

      Volume: 72 Issue: 1 Pages: 161-165

    • DOI

      10.1007/s11418-017-1124-3

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Metabolomic and Proteomic Analysis of the Response of Angelica acutiloba after Herbivore Attack2017

    • Author(s)
      Kato R., Morita Y., Ina A., Tatsuo Y., Tamura T., Tezuka Y., Tanaka K.
    • Journal Title

      Nat. Prod. Comm.

      Volume: 12 Pages: 1547-1551

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 化学生態学的応答を用いたトウキの機能性強化に関する研究2018

    • Author(s)
      中原陽平, 南 和輝, 原田将光, 小野直亮, 金谷重彦, 田中 謙
    • Organizer
      日本薬学会第138年会
    • Related Report
      2017 Annual Research Report
  • [Presentation] キアゲハによる食害を受けたトウキのプロテオーム解析2017

    • Author(s)
      加藤梨紗, 伊奈隆年, 田村隆幸, 田中 謙
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Research-status Report
  • [Presentation] キアゲハの忌避物質に関する研究2017

    • Author(s)
      南 和輝, 阪森宏治, 田 隆幸, 仲島義貴, 西殿悠人, 福井麻琴, 田中陽一郎, 佐藤雅史, 小澤理香, 高林純示, 田中 謙
    • Organizer
      日本薬学会第137年会
    • Place of Presentation
      仙台国際センター(宮城県・仙台市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Research-status Report
  • [Presentation] 薬用植物の化学生態学的応答を用いたトウキの機能性強化に関する研究2016

    • Author(s)
      森田侑介、神野拓也、辰尾良秋、田村隆幸、金谷重彦、田中謙
    • Organizer
      日本薬学会第136年会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2016-03-28
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-12-27  

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