| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Outline of Final Research Achievements |
Intestinal cholesterol absorption is an important process to regulate cholesterol levels in the body. However, molecular mechanisms of cholesterol absorption have not been fully uncovered yet. The aim of this study is to reveal novel regulators of intestinal cholesterol absorption by elucidating mouse substrain difference in efficiency of cholesterol absorption. Since various candidate molecules that might be accounted for the strain difference in cholesterol absorption was found by several proteomics approaches, novel key regulators of intestinal cholesterol absorption would be revealed in the near future.
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