Measurements of cellular mechanics using super resolution microscope
| Project/Area Number |
15K15010
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
General anatomy (including histology/embryology)
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| Research Institution | Hokkaido University |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2015: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 細胞運動 / 力学 / 共同現象 / 生物物理学 / メカノセンス / 細胞協調 |
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| Outline of Final Research Achievements |
During the generation of organs, cells should migrate not in a random walk but in a directional mode (collective migration). In this project, we measured mechanical and biochemical information within collective cell migration, and revealed an aspect of the mechanism of collective migration. As a result, we found that cell-cell junction is essential for the collective migration.
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Report
(3 results)
Research Products
(11 results)
