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Neural mechanisms for transmission of emotional information

Research Project

Project/Area Number 15K15042
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Environmental physiology(including physical medicine and nutritional physiology)
Research InstitutionJichi Medical University

Principal Investigator

Onaka Tatsushi  自治医科大学, 医学部, 教授 (90177254)

Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsオキシトシン受容体 / ストレス / オキシトシン / 情動
Outline of Final Research Achievements

When animals are confronted with animals showing negative emotional responses, these animals show similar negative emotional responses. Transmission of negative emotional states has been considered to play an important role in warning other individuals of the same group against the danger. Oxytocin has been reported to facilitate social behavior possibly by increasing the salience of sociosensory cues. However, neural mechanisms remain unclear. The present study suggests that oxytocin receptor-expressing cells within the cortex were activated during exposure to socially-defeated animals.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2017 2016 2015

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results,  Acknowledgement Compliant: 2 results) Presentation (4 results) (of which Int'l Joint Research: 1 results,  Invited: 2 results)

  • [Journal Article] Activation of supraoptic oxytocin neurons by secretin facilitates social recognition.2015

    • Author(s)
      Takayanagi Y, Yoshida M, Takashima A, Takanami K, Yoshida S, Nishimori K, Nishijima I, Sakamoto H, Yamagata T, Onaka T
    • Journal Title

      Biological Psychiatry

      Volume: in press Issue: 3 Pages: 243-251

    • DOI

      10.1016/j.biopsych.2015.11.021

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Noxious or Non-Noxious Inputs to Oxytocin Neurons: Possible Roles in the Control of Behaviors.2015

    • Author(s)
      Onaka T, Okabe S, Takayanagi Y, Yoshida M
    • Journal Title

      Interdisciplinary Information Sciences

      Volume: 21 Issue: 3 Pages: 189-195

    • DOI

      10.4036/iis.2015.b.03

    • NAID

      110009966527

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Presentation] 社会的敗北とオキシトシン2017

    • Author(s)
      尾仲達史
    • Organizer
      第27回日本行動神経内分泌研究会
    • Place of Presentation
      牛窓研修センターカリヨンハウス(岡山県瀬戸内市)
    • Year and Date
      2017-04-28
    • Related Report
      2016 Annual Research Report
  • [Presentation] オキシトシンとストレス、エネルギー代謝、社会行動2017

    • Author(s)
      尾仲達史
    • Organizer
      第90回日本内分泌学会学術総会
    • Place of Presentation
      ロームシアター京都・京都勧業館みやこめっせ(京都府京都市)
    • Year and Date
      2017-04-20
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] Neuroendocrine and behavioral responses to fear-related or affiliative stimuli: roles of oxytocin.2016

    • Author(s)
      Onaka T, Takayanagi Y, Yoshida M, Okabe S
    • Organizer
      The 93rd Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      札幌
    • Year and Date
      2016-03-22
    • Related Report
      2015 Research-status Report
  • [Presentation] Noxious or Non-Noxious Inputs to Oxytocin Neurons: Possible Roles in the Control of Behaviors.2015

    • Author(s)
      Onaka T, Takayanagi Y, Yoshida M, Okabe S
    • Organizer
      Parvo- and Magnocellular Symposium in Sendai
    • Place of Presentation
      Sendai
    • Year and Date
      2015-09-17
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited

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Published: 2015-04-16   Modified: 2018-03-22  

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