Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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Outline of Final Research Achievements |
Understanding the Life cycle of human hepatitis B virus (HBV), the causal virus of hepatitis and liver cancer, is important in exploring new ways to prevent the infection and proliferation of HBV. In this study, as a foothold to elucidate the molecular mechanism of hepatocyte-specific infection of HBV which is not well understood yet, and as a basis for anti-HBV drug discovery, we established HBV in vitro infection system with more efficient and reproducible effect on differentiated hepatocytes from newly prepared iPS cells.
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