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Development of Cherenkov-based TOF-PET with superior time resolution

Research Project

Project/Area Number 15K15209
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Medical Physics and Radiological Technology
Research InstitutionNagoya University

Principal Investigator

IIJIMA Toru  名古屋大学, 現象解析研究センター, 教授 (80270396)

Research Collaborator KOBAYASHI Kazuho  名古屋大学, 大学院理学研究科, 大学院生
KRIZAN Peter  名古屋大学, 現象解析研究センター, 客員教授
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywords放射線検出器 / TOF-PET / 半導体光検出器
Outline of Final Research Achievements

TOF-PET(Positron Emission Tomography) is one of the most advanced medical imaging technology. which utilizes the TOF( Tme-Of-Fligh) difference between the two annihilation gamma's to reconstruct images with improved signal-to-noise ratio. We have studied possibility to improve the TOF-PET performance using a Cherenkov radiator instead of a scintillator to detect gamma's, as application of technology developed for recent particle physics experiments. We have demonstrated that Cherenkov-based TOF-PET provides TOF resolution of about 120ps, a few times better compared to that reported for a scintillator-based TOF-PET. Our research shows that it is possible to develop high performance TOF-PET with relatively low cost, also by using a semiconductor photodetector device with improved photo detection efficiency and improved time resolution.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (7 results)

All 2016 Other

All Int'l Joint Research (2 results) Presentation (4 results) (of which Int'l Joint Research: 3 results) Remarks (1 results)

  • [Int'l Joint Research] Josef Stefan Institute/Univ. of Ljubljana/Univ. of Maribor(Slovenia)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] Josef Stefan Institute/University of Ljubljana/University of Maribor(Slovenia)

    • Related Report
      2015 Research-status Report
  • [Presentation] Measurements of 511 keV annihilation photons with ultimate timing resolution2016

    • Author(s)
      K. Kobayashi, T. Iijima, R. Dolenec, S. Korpar, P. Krizan, R. Pestotnik, N. Verdel
    • Organizer
      9th International Workshop on Ring Imaging Cherenkov Detectors
    • Place of Presentation
      Bled, Slovenia
    • Year and Date
      2016-09-05
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Ultrafast Detection in Particle Physics and Positron Ultrafast Detection in Particle Physics and Positron Emission Tomography Using SiPMs2016

    • Author(s)
      R. Dolenec, T. Iijima, K. Kobayashi, S. Korpar, P. Krizan, R. Pestotnik, N. Verdel
    • Organizer
      9th International Workshop on Ring Imaging Cherenkov Detectors
    • Place of Presentation
      Bled, Slovenia
    • Year and Date
      2016-09-05
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Cherenkov光を用いたTOF-PETの実現に向けたMPPCの時間分解能の測定2016

    • Author(s)
      小林一帆, 飯嶋 徹、Peter Krizan, Samo Korpar, Rok Dolenec, Rok Pestotnik, Nina Verdel
    • Organizer
      日本物理学会第71回年次大会
    • Place of Presentation
      東北学院大学、仙台
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
  • [Presentation] Improving the Time Resolution in Cherenkov TOF PET with SiPMs2016

    • Author(s)
      R. Dolenec, T. Iijima, K. Kobayashi, S. Korpar, P. Krizan, R. Pestotnik
    • Organizer
      The 14th Vienna Conference on Instrumentation
    • Place of Presentation
      ウィーン、オーストリア
    • Year and Date
      2016-02-15
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Remarks] 名古屋大学大学院理学研究科高エネルギー素粒子物理学研究室 N研

    • URL

      http://www.hepl.phys.nagoya-u.ac.jp/

    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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