| Project/Area Number |
15K15226
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Epidemiology and preventive medicine
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| Research Institution | Yamaguchi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
常岡 英弘 山口大学, 大学院医学系研究科, 教授 (40437629)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2017: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | ネコひっかき病 / N-ラウロイルサルコシン / IgM-ウエスタンブロット / バルトネラ・ヘンセラ / 猫ひっかき病 / ワクチン / 抗原同定 / N-ラウロイルーサルコシン / CSD / バルトネラヘンセラ |
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| Outline of Final Research Achievements |
Based on the antigen extraction method using N-Lauroylsarcosine that we developed Bartonella henselae, the causative fungus of cat scratch disease (CSD), an antigen sensitive to patient's serum sensitivity I succeeded in doing. Antigen reacting specifically to the patient for the first time in the world by this analysis using IgM Western blot and SDS-PAGE from this antigen could be classified into 3 to 4 groups from the molecular weight. Currently, identification of this specific antigen is underway.
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