• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Reset of the epigenetic abnormality by dietary factors for cancer prevention

Research Project

Project/Area Number 15K15235
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Hygiene and public health
Research InstitutionMie University

Principal Investigator

Murata Mariko  三重大学, 医学系研究科, 教授 (10171141)

Co-Investigator(Kenkyū-buntansha) 翠川 薫  三重大学, 医学系研究科, リサーチアソシエイト (20393366)
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywords癌 / 食餌性因子 / DNA損傷 / エピゲノム異常 / DNAメチル化
Outline of Final Research Achievements

Environmental factors including infection and inflammation induce the alteration of genome and epigenome, which may lead to carcinogenesis. Several reports suggest that dietary factors may change the status. First, we examined methods for quantification of DNA methylation, and we could get DNA methylation rates of candidate genes by Bisulfite Amplicon Sequencing (BAS) with high accuracy. In the endemic area of Epstein-Barr virus-associated nasopharyngeal carcinoma, there is an area having low incidence, and their custom of drinking tea attract attention. So, we are checking the effects of tea polyphenol, epigallocatechin gallate (EGCG) on DNA methylation rates and gene expression levels in human nasopharyngeal carcinoma cell lines.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (65 results)

All 2017 2016 2015 Other

All Int'l Joint Research (4 results) Journal Article (17 results) (of which Int'l Joint Research: 11 results,  Peer Reviewed: 17 results,  Acknowledgement Compliant: 8 results,  Open Access: 11 results) Presentation (43 results) (of which Int'l Joint Research: 4 results,  Invited: 1 results) Book (1 results)

  • [Int'l Joint Research] 広西医科大学(中国)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] コンケン大学(タイ)

    • Related Report
      2016 Annual Research Report
  • [Int'l Joint Research] 広西医科大学(中国)

    • Related Report
      2015 Research-status Report
  • [Int'l Joint Research] コンケン大学(タイ)

    • Related Report
      2015 Research-status Report
  • [Journal Article] Plasma protein profiling for potential biomarkers in the early diagnosis of Alzheimer's disease.2017

    • Author(s)
      Kitamura Y, Usami R, Ichihara S, Kida H, Satoh M, Tomimoto H, Murata M, Oikawa S.
    • Journal Title

      Neurol Res.

      Volume: 39 Issue: 3 Pages: 231-238

    • DOI

      10.1080/01616412.2017.1281195

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Nitrative and oxidative DNA damage in infection-related carcinogenesis in relation to cancer stem cells.2017

    • Author(s)
      Kawanishi S, Ohnishi S, Ma N, Hiraku Y, Oikawa S, Murata M.
    • Journal Title

      Genes Environ

      Volume: 38 Issue: 1 Pages: 26-26

    • DOI

      10.1186/s41021-016-0070-8

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] APOE Genotype in the Ethnic Majority and Minority Groups of Laos and the Implications for Non-Communicable Diseases.2016

    • Author(s)
      Midorikawa K, Soukaloun D, Akkhavong K, Southivong B, Rattanavong O, Sengkhygnavong V, Pyaluanglath A, Sayasithsena S, Nakamura S, Midorikawa Y, Murata M.
    • Journal Title

      PLoS One

      Volume: 11 Issue: 5 Pages: 1-15

    • DOI

      10.1371/journal.pone.0155072

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Epigenetic inactivation of follistatin-like 1 mediates tumor immune evasion in nasopharyngeal carcinoma.2016

    • Author(s)
      Zhou X, Xiao X, Huang T, Du C, Wang S, Mo Y, Ma N, Murata M, Li B, Wen W, Huang G, Zeng X, Zhang Z
    • Journal Title

      Oncotarget

      Volume: 7 Issue: 13 Pages: 16433-16444

    • DOI

      10.18632/oncotarget.7654

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Inflammation-related DNA damage and cancer stem cell markers in nasopharyngeal carcinoma.2016

    • Author(s)
      Wang S, Ma N, Zhao W, Midorikawa K, Kawanishi S, Hiraku Y, Oikawa S, Zhang Z, Huang GW, Murata M.
    • Journal Title

      Mediators Inflamm.

      Volume: 2016 Pages: 9343460-9343460

    • DOI

      10.1155/2016/9343460

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Glutaredoxin 3 promotes nasopharyngeal carcinoma growth and metastasis via EGFR/Akt pathway and independent of ROS.2016

    • Author(s)
      He F, Wei L, Luo W, Liao Z, Li B, Zhou X, Xiao X, You J, Chen Y, Zheng S, Li P, Murata M, Huang G, Zhang Z
    • Journal Title

      Oncotarget.

      Volume: 7 Issue: 24 Pages: 37000-37012

    • DOI

      10.18632/oncotarget.9454

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] DNA damage in CD133-positive cells in Barrett’s esophagus and esophageal adenocarcinoma.2016

    • Author(s)
      Thanan R, Ma N, Hiraku Y, Iijima K, Koike T, Shimosegawa T, Murata M, Kawanishi S.
    • Journal Title

      Mediators Inflamm

      Volume: 2016 Pages: 7937814-7937814

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation.2016

    • Author(s)
      Hiraku Y, Guo F, Ma N, Yamada T, Wang S, Kawanishi S, Murata M.
    • Journal Title

      Part Fibre Toxicol.

      Volume: 13 Issue: 1 Pages: 16-16

    • DOI

      10.1186/s12989-016-0127-7

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] DNA Damage in CD133-Positive Cells in Barrett's Esophagus and Esophageal Adenocarcinoma.2016

    • Author(s)
      Thanan R, Ma N, Hiraku Y, Iijima K, Koike T, Shimosegawa T, Murata M, Kawanishi S.
    • Journal Title

      Mediators Inflamm.

      Volume: 2016 Pages: 7937814-7937814

    • DOI

      10.1155/2016/7937814

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Epigenetic downregulation of the ISG15-conjugating enzyme UbcH8 impairs lipolysis and correlates with poor prognosis in nasopharyngeal carcinoma.2015

    • Author(s)
      Zhou X, Wei J, Chen F, Xiao X, Huang T, He Q, Wang S, Du C, Mo Y, Lin L, Xie Y, Wei L, Lan Y, Murata M, Huang G, Ernberg I, Matskova L, Zhang Z.
    • Journal Title

      Oncotarget.

      Volume: 6(38) Issue: 38 Pages: 41077-1091

    • DOI

      10.18632/oncotarget.6218

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] The potent tumor suppressor miR-497 inhibits cancer phenotypes in nasopharyngeal carcinoma by targeting ANLN and HSPA4L.2015

    • Author(s)
      Wang S, Mo Y, Midorikawa K, Zhang Z, Huang G, Ma N, Zhao W, Hiraku Y, Oikawa S, Murata M.
    • Journal Title

      Oncotarget

      Volume: 6 Issue: 34 Pages: 35893-35907

    • DOI

      10.18632/oncotarget.5651

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Development and characterization of a hydrogen peroxide-resistant cholangiocyte cell line: A novel model of oxidative stress-related cholangiocarcinoma genesis.2015

    • Author(s)
      Thanan R, Techasen A, Hou B, Jamnongkan W, Armartmuntree N, Yongvanit P, Murata M.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 64(1) Issue: 1 Pages: 182-188

    • DOI

      10.1016/j.bbrc.2015.06.112

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Oxidative DNA damage induced by metabolites of chloramphenicol, an antibiotic drug.2015

    • Author(s)
      Ohnishi S, Murata M, Ida N, Oikawa S, Kawanishi S.
    • Journal Title

      Free Radic Res.

      Volume: 49 Issue: 9 Pages: 1165-1172

    • DOI

      10.3109/10715762.2015.1050963

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Changes of microRNAs in asymptomatic subjects sensitized to Japanese cedar pollen following prophylactic sublingual immunotherapy.2015

    • Author(s)
      Hou B, Murata M, Shah SA, Sakaida H, Masuda S, Takahashi T, Zhang Z, Takeuchi K.
    • Journal Title

      Allergy Rhinol.

      Volume: 6 Issue: 1 Pages: 33-38

    • DOI

      10.2500/ar.2015.6.0107

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Acknowledgement Compliant
  • [Journal Article] Reduced coenzyme Q10 decreases urinary of 8-oxo-7,8-dihydro-2’-deoxyguanosine concentrations in healthy young female subjects.2015

    • Author(s)
      Ito K, Watanabe C, Nakamura A, Oikawa-Tada S, Murata M.
    • Journal Title

      J Med Food

      Volume: in press Issue: 8 Pages: 835-840

    • DOI

      10.1089/jmf.2014.3302

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Circulating microRNAs as novel prognosis biomarkers for head and neck squamous cell carcinoma.2015

    • Author(s)
      Hou B, Ishinaga H, Midorikawa K, Shah SA, Nakamura S, Hiraku Y, Oikawa S, Murata M, Takeuchi K.
    • Journal Title

      Cancer Biol Ther.

      Volume: 16(7) Pages: 1042-1046

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] Inflammation-related DNA damage in relation to the expression of cancer stemness markers in human nasopharyngeal carcinoma.2015

    • Author(s)
      Wang S, Ma N, Kawanishi S, Zhao W, Midorikawa K, Hiraku Y, Oikawa S, Zhang Z, Huang G, Murata M.
    • Journal Title

      Free Radic Biol Med

      Volume: 86

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Presentation] インジウム曝露ラット肺における遺伝子発現の網羅的解析2017

    • Author(s)
      平工雄介、田中昭代、平田美由紀、村田真理子
    • Organizer
      第87 回日本衛生学会学術総会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 軽度認知障害の診断バイオマーカーの探索2017

    • Author(s)
      北村祐貴、近藤志織、本城貴志、山嶋哲盛、村田真理子、及川伸二
    • Organizer
      第87 回日本衛生学会学術総会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] uantitative comparison of DNA methylation for biomarker in Epstein-Barr virus-associated nasopharyngeal carcinoma.2017

    • Author(s)
      Weilin Zhao, Kaoru Midorikawa, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Mariko Murata.
    • Organizer
      第87 回日本衛生学会学術総会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] Let-7c inhibits migration and epithelial-mesenchymal transition by targeting IGF1R and HMGA2 in head and neck cancer cells.2017

    • Author(s)
      Bo Hou, Kaoru Midorikawa, Yusuke Hiraku, Shinji Oikawa, Ning Ma, Mariko Murata.
    • Organizer
      第87 回日本衛生学会学術総会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] 寄生虫感染による膀胱癌患者組織における炎症関連DNA損傷とCOX2発現.2017

    • Author(s)
      大西志保、馬寧、村田真理子、平工雄介・及川伸二、小林果、川西正祐.
    • Organizer
      第87 回日本衛生学会学術総会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] Increased expression of Glutaredoxin 3 promotes the proliferation and metastasis of nasopharyngeal carcinoma.2017

    • Author(s)
      Feng He, Kaoru Midorikawa, Yusuke Hiraku, Shinji Oikawa, Ning Ma, Mariko Murata.
    • Organizer
      第87 回日本衛生学会学術総会
    • Place of Presentation
      シーガイアコンベンションセンター(宮崎県宮崎市)
    • Year and Date
      2017-03-26
    • Related Report
      2016 Annual Research Report
  • [Presentation] ラオスにおけるAPOE遺伝子型と生活習慣病2017

    • Author(s)
      翠川薫、中村哲、翠川裕、村田真理子
    • Organizer
      第16回分子予防環境医学研究会
    • Place of Presentation
      熊本市国際交流会館(熊本県熊本市)
    • Year and Date
      2017-02-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] 2D-DIGE 法を用いた軽度認知障害患者の血漿タンパク質のプロファイリング2017

    • Author(s)
      近藤志織、北村祐貴、本城貴志、山嶋哲盛、村田真理子、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第 5 回学術集会
    • Place of Presentation
      愛知学院大学名城公園キャンパス(愛知県名古屋市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 化損傷タンパク質を指標としたアルツハイマー病のバイオマーカーの探索2017

    • Author(s)
      辻本佳世、北村祐貴、木田博隆、佐藤正之、市原佐保子、埜村 智之、 石川雅一、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第 5 回学術集会
    • Place of Presentation
      愛知学院大学名城公園キャンパス(愛知県名古屋市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] NNKが誘導したマウス肺がんに対するヤマブドウ抽出画分の肺発がん抑制効果に関与するタンパク質の同定2016

    • Author(s)
      北村祐貴、三宅直子、有元佐賀惠、村田真理子、及川伸二
    • Organizer
      第45回日本環境変異原学会
    • Place of Presentation
      つくば国際会議場(茨城県つくば市)
    • Year and Date
      2016-11-17
    • Related Report
      2016 Annual Research Report
  • [Presentation] Nitrative DNA damage induced by multi-walled carbon nanotube in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation.2016

    • Author(s)
      Yusuke Hiraku, Feiye Guo, Ning Ma, Tatsuhiko Yamada, Shumin Wang, Shosuke Kawanishi, Mariko Murata
    • Organizer
      11th International Particle Toxicology Conference
    • Place of Presentation
      Biopolis Matrix(Singapore)
    • Year and Date
      2016-09-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Tumor suppressing roles of let-7c in head and neck cancer.2016

    • Author(s)
      Bo Hou, Hajime Ishinaga, Kaoru Midorikawa, Ning Ma, Weilin Zhao, Shinji Oikawa, Yusuke Hiraku, Kazuhiko Takeuchi, Mariko Murata
    • Organizer
      he 7th EMBO meeting 2016
    • Place of Presentation
      Congress Center Rosengarten Mannheim(Mannheim, Germany)
    • Year and Date
      2016-09-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] パーキンソン病患者血漿中のカルボニル化タンパク質の解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      第69回日本酸化ストレス学会学術集会
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-08-30
    • Related Report
      2016 Annual Research Report
  • [Presentation] タバコ特異的ニトロサミンNNK誘導マウス肺がんに対するヤマブドウ成分の発がん抑制効果における比較プロテオミクス解析2016

    • Author(s)
      北村祐貴、有元佐賀惠、谷本雄亮、久保寿夫、木浦勝行、村田真理子、及川伸二
    • Organizer
      第23回日本がん予防学会総会
    • Place of Presentation
      名古屋大学鶴舞キャンパス(愛知県名古屋市)
    • Year and Date
      2016-07-01
    • Related Report
      2016 Annual Research Report
  • [Presentation] インジウム曝露ラット肺におけるマイクロRNAと標的遺伝子の発現解析2016

    • Author(s)
      平工雄介、田中昭代、平田美由紀、村田真理子
    • Organizer
      第89回日本産業衛生学会
    • Place of Presentation
      福島市音楽堂(福島県福島市)
    • Year and Date
      2016-05-24
    • Related Report
      2016 Annual Research Report
  • [Presentation] インジウム曝露ラット肺におけるマイクロRNA発現の網羅的解析と標的遺伝子の探索2016

    • Author(s)
      平工雄介、田中昭代、平田美由紀、村田真理子
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] パーキンソン病の血漿中エクソソームのプロテオミクス解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] インジウム化合物で処理したマクロファージ培養細胞におけるニトロ化DNA損傷2016

    • Author(s)
      Tahmina Afroz、馬寧、川西正祐、村田真理子、平工雄介
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] Let-7c functions as a tumor suppressor by targeting IGF1R in head and neck cancer.2016

    • Author(s)
      Bo Hou, Kaoru Midorikawa, Yusuke Hiraku, Shinji Oikawa, Ning Ma, Mariko Murata.
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] Hypermethylation of RERG promoter in nasopharyngeal carcinoma.2016

    • Author(s)
      Weilin Zhao, Shumin Wang, Kaoru Midorikawa, Ning Ma, Yusuke Hiraku , Shinji Oikawa, Mariko Murata.
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2016 Annual Research Report
  • [Presentation] ンジウム化合物で処理したマクロファージ培養細胞におけるニトロ化DNA損傷2016

    • Author(s)
      Tahmina Afroz、馬寧、川西正祐、村田真理子、平工雄介
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2015 Research-status Report
  • [Presentation] Let-7c functions as a tumor suppressor by targeting IGF1R in head and neck cancer.2016

    • Author(s)
      Bo Hou, Kaoru Midorikawa, Yusuke Hiraku, Shinji Oikawa, Ning Ma, Mariko Murata.
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2015 Research-status Report
  • [Presentation] Hypermethylation of RERG promoter in nasopharyngeal carcinoma.2016

    • Author(s)
      Weilin Zhao, Shumin Wang, Kaoru Midorikawa, Ning Ma, Yusuke Hiraku, Shinji Oikawa, Mariko Murata.
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2015 Research-status Report
  • [Presentation] インジウム曝露ラット肺におけるマイクロRNA発現の網羅的解析と標的遺伝子の探索2016

    • Author(s)
      平工雄介、田中昭代、平田美由紀、村田真理子
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2015 Research-status Report
  • [Presentation] パーキンソン病患者の血漿中エクソソームを用いたバイオマーカーの探索2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      第86回日本衛生学会総会
    • Place of Presentation
      旭川市民文化会館(北海道旭川市)
    • Year and Date
      2016-05-11
    • Related Report
      2015 Research-status Report
  • [Presentation] パーキンソン病患者血漿中の酸化損傷タンパク質の解析2016

    • Author(s)
      北村祐貴、佐々木良元、市原佐保子、埜村智之、石川雅一、水野章、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本酸化ストレス学会東海支部第4回学術大会
    • Place of Presentation
      鈴鹿医療科学大学(三重県鈴鹿市)
    • Year and Date
      2016-02-06
    • Related Report
      2015 Research-status Report
  • [Presentation] 発がんにおけるDNA損傷とエピゲノム異常の役割:上咽頭癌での検討.2016

    • Author(s)
      村田真理子
    • Organizer
      日本耳鼻咽喉科学会中部地方会連合会
    • Place of Presentation
      津都ホテル(三重県津市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 筋萎縮性側索硬化症の脳脊髄液における酸化損傷タンパク質の同定2016

    • Author(s)
      北村祐貴、菰田淳、二本松綾乃、佐々木良元、村田真理子、冨本秀和、及川伸二
    • Organizer
      第80回日本生化学会中部支部例会・シンポジウム
    • Place of Presentation
      三重大学講堂(三重県津市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] ヒト肺組織における石綿繊維量とニトロ化DNA損傷との関連2016

    • Author(s)
      平工雄介、酒井潔、柴田英治、上島通浩、久永直見、村田真理子
    • Organizer
      第62回東海公衆衛生学会学術大会
    • Place of Presentation
      穂の国とよはし芸術劇場16プラット(愛知県豊橋市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] タバコ煙中発がん物質による肺がんマウスに対するサルナシ果汁の発がん抑制効果における比較プロテオミクス解析2016

    • Author(s)
      北村祐貴、三宅直子、有元佐賀惠、村田真理子、及川伸二
    • Organizer
      第62回東海公衆衛生学会学術大会
    • Place of Presentation
      穂の国とよはし芸術劇場プラット(愛知県豊橋市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] インジウム化合物に曝露した培養細胞におけるニトロ化DNA損傷2016

    • Author(s)
      平工雄介、Tahmina Afroz、馬寧、川西正祐、村田真理子
    • Organizer
      日本産業衛生学会東海地方会
    • Place of Presentation
      浜松医科大学(静岡県浜松市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] NNK誘導マウス肺がんに対するサルナシ果汁の肺発がん抑制効果における比較プロテオミクス解析2015

    • Author(s)
      北村祐貴、三宅直子、有元佐賀惠、村田真理子、及川伸二
    • Organizer
      第44回日本環境変異原学会
    • Place of Presentation
      九州大学馬出キャンパス(福岡県福岡市)
    • Year and Date
      2015-11-27
    • Related Report
      2015 Research-status Report
  • [Presentation] インジウム曝露ラット肺におけるマイクロRNA発現の解析と標的遺伝子の探索2015

    • Author(s)
      平工雄介、黒澤長之、田中昭代、平田美由紀、村田真理子
    • Organizer
      日本産業衛生学会東海地方会
    • Place of Presentation
      名古屋大学医学部(愛知県名古屋市)
    • Year and Date
      2015-11-14
    • Related Report
      2015 Research-status Report
  • [Presentation] Early B cell factor 1 down-regulation mechanisms and their significance in cholangiocarcinoma prognosis.2015

    • Author(s)
      Napat Armartmuntree、Chakkaphan Khenjanta、Wassana Jamnongkan、Anchalee Techasen、Watcharin Loilome、Nisana Namwat、Somchai Pinlaor、Chawalit Pairojkul、Puangrat Yongvanit、Murata, Mariko、Thanan, Raynoo
    • Organizer
      第74 回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Genome-wide profiling of DNA methylation identifies oxidative stress-induced epigenetic targets in cholangiocarcinoma.2015

    • Author(s)
      Raynoo Thanan、Somchai Pinlaor、Umawadee Laothong、Puangrat Yongvanit、Ning Ma、Shosuke Kawanishi、Mariko Murata
    • Organizer
      第74 回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] 頭頸部扁平上皮癌におけるマイクロRNA let-7c とその標的遺伝子の役割.2015

    • Author(s)
      侯波、石永一、翠川薫、王淑民、趙蔚林、及川伸二、平工雄介、馬寧、竹内万彦、村田真理子
    • Organizer
      第74 回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] 上咽頭癌における癌抑制遺伝子候補のプロモーター領域DNA の高度メチル化.2015

    • Author(s)
      趙蔚林、王淑民、翠川薫、張哲、莫頴禧、黄光武、馬寧、平工雄介、及川伸二、村田真理子
    • Organizer
      第74 回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Nitrative DNA damage in lung epithelilal cells treated with multi-walled carbon nanotube: role of Toll-like receptor 92015

    • Author(s)
      Yusuke Hiraku, Ning Ma, Shumin Wang, Shosuke Kawanishi, Mariko Murata
    • Organizer
      第74回日本癌学会学術総会
    • Place of Presentation
      名古屋国際会議場(愛知県名古屋市)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
  • [Presentation] Inflammation-related DNA damage in relation to the expression of cancer stemness markers in human nasopharyngeal carcinoma.2015

    • Author(s)
      Wang S, Ma N, Kawanishi S, Zhao W, Midorikawa K, Hiraku Y, Oikawa S, Zhang Z, Huang G, Murata M.
    • Organizer
      SFRR-E/SNFS Meeting Stuttgart 2015: Redox Biology Meets Nutrition
    • Place of Presentation
      ホ-エンハイム大学,シュトゥットガルト(ドイツ)
    • Year and Date
      2015-09-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 筋萎縮性側索硬化症の脳脊髄液におけるカルボニル化タンパク質の解析2015

    • Author(s)
      北村祐貴、菰田淳、二本松綾乃、佐々木良元、村田真理子、冨本秀和、及川伸二
    • Organizer
      日本プロテオーム学会2015年会
    • Place of Presentation
      熊本森都心プラザ(熊本県熊本市)
    • Year and Date
      2015-07-23
    • Related Report
      2015 Research-status Report
  • [Presentation] Novel circulating microRNA biomarkers for head and neck squamous cell carcinoma.2015

    • Author(s)
      Bo Hou, Hajime Ishinaga, Said Ahmad Shah, Satoshi Nakamura, Kaoru Midorikawa, Mariko Murata, Kazuhiko Takeuchi.
    • Organizer
      4th Congress of Asian Society of Head and Neck Oncology
    • Place of Presentation
      神戸国際会議場(兵庫県神戸市)
    • Year and Date
      2015-06-03
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Possible roles of circulating microRNAs during prophylactic sublingual immunotherapy.2015

    • Author(s)
      Bo Hou, Mariko murata, Hiroshi Sakaida, Sawako Masuda, Kazuhiko Takeuchi.
    • Organizer
      第64回日本アレルギー学会学術大会
    • Place of Presentation
      グランドプリンスホテル新高輪 国際館パミール(東京都港区)
    • Year and Date
      2015-05-26
    • Related Report
      2015 Research-status Report
  • [Presentation] インジウム曝露ラット肺におけるマイクロRNA発現の網羅的解析2015

    • Author(s)
      平工雄介、田中昭代、平田美由紀、村田真理子
    • Organizer
      第88回日本産業衛生学会
    • Place of Presentation
      グランフロント大阪(大阪府大阪市)
    • Year and Date
      2015-05-13
    • Related Report
      2015 Research-status Report
  • [Book] Molecular Aspects of Alcohol and Nutrition: A Volume in the Molecular Nutrition Series.2016

    • Author(s)
      Murata M, Midorikawa K, Kawanishi S.
    • Total Pages
      376
    • Publisher
      Vinood Patel. Elsevier Science & Technology
    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi