Development of metal nano particle-based infection control system
| Project/Area Number |
15K15253
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Medical and hospital managemen
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| Research Institution | Juntendo University |
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Principal Investigator |
SEKINE MIWA 順天堂大学, 医学(系)研究科(研究院), 助教 (10398670)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | ナノ粒子 / 黄色ブドウ球菌 / 院内感染 / 感染対策 / 細胞毒性 / 殺菌活性 |
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| Outline of Final Research Achievements |
The goal of this research is to develop simpler and more effective infection prevention system for the prevalence of widespread nosocomial infection and expansion of drug resistant Staphylococcus aureus such as VISA (Methicillin-resistant strain with vancomycin-intermediate resistance) infection.
The main achievements are as follows; 1) Confirming the bactericidal effect and bacteriostatic effect of platinum nanoparticles, 2) Discovering the platinum nanoparticle dispersion has little or no cytotoxicity on conventional cultured human cells, 3) Finding that platinum nanoparticle dispersion does not induce inflammatory cytokine secretion. These results revealed that it is highly possible that protection against infection by platinum nanoparticles can be effective.
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Report
(4 results)
Research Products
(2 results)
