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An investigation of incidence and profiles of patients with MUS in Japan

Research Project

Project/Area Number 15K15275
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field General internal medicine(including psychosomatic medicine)
Research InstitutionKagawa University

Principal Investigator

Okada Hiroki  香川大学, 医学部, 教授 (00243775)

Co-Investigator(Kenkyū-buntansha) 西屋 克己  香川大学, 医学部, 准教授 (60526838)
舛形 尚  香川大学, 医学部附属病院, 教授 (70263910)
釋 文雄  日本大学, 医学部, 助教 (90647976)
Research Collaborator MATSUMOTO Kaori  
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords不定愁訴 / MUS / 身体感覚増幅 / QOL / 疾患知覚 / 身体的健康尺度 / 精神的健康尺度 / 疾患認識 / 医学的に説明できない症状 / 頻度調査 / 疼痛障害 / 倦怠感 / しびれ感
Outline of Final Research Achievements

We performed following investigations about patients with MUS.
1)Incidence:The first-visit patients in 22 institutes were asked to write down the symptoms they felt at the time of their visit. Then doctors judged those symptoms to determine whether those were medically explainable or not. The data of 1432 patients (mean age;46.6y-o) were collected. The percentages of patients with MUS in all subjects, clinics, small hospitals, and large hospitals was 25%, 16.5%, 14.7%, and 41.7%, respectively. Frequent symptoms were pain(19.6%), fatigue(6.3%), fever(3.9%), numbness(3.5%), vertigo(3.2%), nausea(2.5%), appetite loss(2.0%) and so on.
2)Patient profile:The subjects were outpatients visiting psychosomatic institutes. Measurements of somatosensory amplification (SA), physical and mental QOL(measured by SF-8), illness perception (IP) scale, and mood disturbance (MD) scale were examined. SA, IP, MD was highest in patients with depression, and QOL was lowest in those patients.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (6 results)

All 2016 2015

All Journal Article (1 results) Presentation (4 results) (of which Int'l Joint Research: 1 results) Funded Workshop (1 results)

  • [Journal Article] 海外での不定愁訴診療の現状とは?2015

    • Author(s)
      岡田 宏基
    • Journal Title

      Modern Physician

      Volume: 35 Pages: 993-6

    • Related Report
      2015 Research-status Report
  • [Presentation] 医学的に説明できない症候(MUS)の香川県を中心とした頻度調査について2016

    • Author(s)
      岡田宏基、西屋克己、舛形尚、釋文雄、松元かおり
    • Organizer
      第21回日本心療内科学会総会・学術大会
    • Place of Presentation
      奈良市
    • Year and Date
      2016-12-03
    • Related Report
      2016 Annual Research Report
  • [Presentation] 医学的に説明できない症候(MUS)の香川県を中心とした頻度調査について2016

    • Author(s)
      岡田宏基、西屋克己、舛形尚、釋文雄、松元かおり
    • Organizer
      第13回日本病院総合診療医学会学術総会
    • Place of Presentation
      東京都
    • Year and Date
      2016-09-16
    • Related Report
      2016 Annual Research Report
  • [Presentation] 現代版不定愁訴MUS(Medically Unexplained Symptoms)の香川県を中心とした頻度調査報告2016

    • Author(s)
      岡田宏基、西屋克己、舛形尚、釋文雄、松元かおり
    • Organizer
      平成28年度香川県医学会
    • Place of Presentation
      高松市
    • Related Report
      2016 Annual Research Report
  • [Presentation] The Possibility of Kampo Application for the Initial Treatment of Medically Unexplained Symptoms2015

    • Author(s)
      Hiroki Okada
    • Organizer
      23ed World Congress of Psychosomatic Medicine
    • Place of Presentation
      Glasgow, Scotland
    • Year and Date
      2015-08-20
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Funded Workshop] 23rd World Congress of Psychosomatic Medicine2015

    • Place of Presentation
      Glasgow, Scotland
    • Year and Date
      2015-08-19
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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