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A brain study of emotion evoked by opening eyes wide passively

Research Project

Project/Area Number 15K15279
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field General internal medicine(including psychosomatic medicine)
Research InstitutionTokyo Medical University

Principal Investigator

SASAKI MITSUYOSHI  東京医科大学, 医学部, 教授 (10170698)

Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥2,990,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥690,000)
Fiscal Year 2016: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords表情 / 機能的磁気共鳴画像 / 気分プロフィール検査
Outline of Final Research Achievements

The passive change of the facial expression using their fingers affected the mood. Especially, opening eyes wide increased a positive mood. When measuring the brain waves, alpha waves emerged during opening eyes wide. It puzzled us since alpha waves usually appear during closing eyes and disappear during opening one’s eyes. Then we investigated the brain activity with a functional magnetic resonance imaging. The result showed that the opening eyes wide deactivated a wide area of the frontal pole cortex. This seemed to be consistent with the emergence of alpha waves: brain activities are lower at alpha waves than at beta ones. Opening eyes wide might calm down the actively working frontal pole cortex that is suggested to explore the relative value of novel alternative strategies toward more advanced goal-directed behaviors.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2017 2016

All Presentation (4 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] Deactivation of the frontal pole cortex caused by opening eyes wide passively: an fMRI study2017

    • Author(s)
      Mitsuyoshi Sasaki, Yoichi Araki, Nobutaka Yoshimura, Mana Yoshimura, Yukiko K. Hayashi
    • Organizer
      第94回日本生理学会大会
    • Place of Presentation
      アクトシティ浜松
    • Year and Date
      2017-03-28
    • Related Report
      2016 Research-status Report
  • [Presentation] 受動的に目を大きく開くことにより前頭極の活動が低下する。2017

    • Author(s)
      佐々木光美、荒木洋一、吉村宣高、吉村真奈、林由起子
    • Organizer
      日本生理学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] Deactivation of the frontal pole cortex caused by opening eyes wide passively: an fMRI study2017

    • Author(s)
      Mitsuyoshi Sasaki, Yoichi Araki, Nobutaka Yoshimura, Mana Yoshimura, Yukiko K. Hayashi
    • Organizer
      World Congress of Neurology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] The assessment of emotion evoked by passive change of facial expression.2016

    • Author(s)
      Sasaki Mitsuyoshi
    • Organizer
      The 93rd Annual Meeting of the Physiological Society of Japan
    • Place of Presentation
      Sapporo
    • Year and Date
      2016-03-22
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2019-03-29  

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