| Project/Area Number |
15K15410
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Dermatology
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| Research Institution | Niigata University |
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Principal Investigator |
Abe Riichiro 新潟大学, 医歯学系, 教授 (60344511)
|
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| Project Period (FY) |
2015-04-01 – 2016-03-31
|
| Project Status |
Completed (Fiscal Year 2015)
|
| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2015: ¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
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| Keywords | ミトコンドリア / 角化 |
|---|
| Outline of Final Research Achievements |
Keratinization is an important process in epidermis, and contribute to barrier function. At present it is not well known about a detail mechanism of keratinization, Mitichondria contiributes various cell maintenance.
In this project, we aimed to unreveal that mechanism. We generated the mice lacking important gene in skin to keep mitochondrial function to analyze the role of mitochondria in keratinization.
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