Development of a Technology to Quantify Psychiatric Symptoms Utilizing Behavioral and Physiological Data
| Project/Area Number |
15K15434
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Psychiatric science
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| Research Institution | Keio University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
三村 將 慶應義塾大学, 医学部(信濃町), 教授 (00190728)
江口 洋子 慶應義塾大学, 医学部(信濃町), 研究員 (70649524)
藤田 卓仙 名古屋大学, 経済学研究科, 寄附講座准教授 (80627646)
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| Research Collaborator |
YOSHIMURA Michitaka
KITAZAWA Momoko
LIANG Kuo-ching
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | うつ病 / 機械学習 / 行動 / 生理 / 表情解析 / 躁うつ病 / 音声解析 / 生活活動 / 脳神経疾患 / 表情 / 定量化 |
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| Outline of Final Research Achievements |
Since there is no established biomarkers that reflect the severity of psychiatric disorders, there are problems such as low diagnosis agreement, difficulty in understanding the therapeutic effect in psychiatry. In this study, we examined whether it is possible to develop an machine learning algorithm for quantifying psychiatric symptoms using voice and images analyses. We interviewed patients with major depressive disorder/bipolar disorder and videotaped it. Machine learning was performed based on the collected voice/facial image data, and it was found that the presence or absence of depressive symptoms, its severity could be estimated with a certain degree of accuracy.
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| Academic Significance and Societal Importance of the Research Achievements |
音声や画像データに基づく重症度評価が可能になれば、時間がかかる、負担が大きいなどで臨床で省略されがちな重症度評価が簡便に行えるようになり、治療効果の定量を通じて、より効果的な治療が選択されることにつながったり、ひいては新薬の開発が容易になったりする可能性がある。さらには、発病前の段階でのセルフケアツールとしても活用可能になれば、社会費用が甚大なうつ病の予防効果も期待できるようになる。
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Report
(4 results)
Research Products
(71 results)
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[Journal Article] Attenuated psychotic and basic symptom characteristics in adolescents with ultra-high risk criteria for psychosis, other non-psychotic psychiatric disorders and early-onset psychosis.2016
Author(s)
Lo Cascio N, Saba R, Hauser M, Vernal DL, Al-Jadiri A, Borenstein Y, Sheridan EM, Kishimoto T, Armando M, Vicari S, Fiori Nastro P, Girardi P, Gebhardt E, Kane JM, Auther A, Carrion RE, Cornblatt BA, Schimmelmann BG, Schultze-Lutter F, Correll CU.
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Journal Title
Eur Child Adolesc Psychiatry
Volume: 25
Pages: 1091-1102
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Predictors of readmission after successful electroconvulsive therapy for depression: a chart review study.2016
Author(s)
Uchida T, Kishimoto T, Koreki A, Nakao S, Owada A, Koizumi T, Saito A, Sato M, Sawada S, Matsuzaki R, Petrides G, Mimura M.
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Journal Title
Int J Psychiatry Clin Pract
Volume: 20
Pages: 260-264
Related Report
Peer Reviewed / Int'l Joint Research
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[Journal Article] Frequency and correlates of DSM-5 attenuated psychosis syndrome in a sample of adolescent inpatients with nonpsychotic psychiatric disorders.2015
Author(s)
Gerstenberg M, Hauser M, Al-Jadiri A, Sheridan EM, Kishimoto T, Borenstein Y, Vernal DL, David L, Saito E, Landers SE, Carella M, Singh S, Carbon M, Jiménez-Fernández S, Birnbaum ML, Auther A, Carrión RE, Cornblatt BA, Kane JM, Walitza S, Correll CU
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Journal Title
J Clin Psychiatry
Volume: 76
Issue: 11
Pages: 1449-1458
DOI
Related Report
Peer Reviewed / Int'l Joint Research
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[Presentation] 部分断眠における表情への影響2017
Author(s)
吉村道孝, 元村祐貴, 勝沼るり, 北沢桃子, 岸本泰士郎, 坪田一男, 三島一男
Organizer
第23回日本行動医学会学術総会
Place of Presentation
沖縄科学技術大学院大学（沖縄県国頭郡恩納村）
Year and Date
2017-03-17
Related Report
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[Presentation] 維持期治療2016
Author(s)
岸本泰士郎
Organizer
第112回日本精神神経学会学術総会
Place of Presentation
幕張メッセ（千葉県千葉市）
Year and Date
2016-06-02
Related Report
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[Presentation] うつ病に対する修正型電気けいれん療法後の再入院予測因子：診療録調査2015
Author(s)
内田貴仁, 岸本泰士郎, 是木明宏, 中尾重嗣, 大和田藍, 小泉輝樹, 齋藤篤之, 鹿島美納子, 澤田真也, 松崎竜太, Georgious Petrides, 三村將
Organizer
第28回日本総合病院精神医学会総会
Place of Presentation
あわぎんホール（徳島県徳島市）
Year and Date
2015-11-27
Related Report
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