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99Mo/99mTc generator development aiming for domestic production of 99Mo/99mTc for the first time in Japan

Research Project

Project/Area Number 15K15445
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionUniversity of Tsukuba

Principal Investigator

FUKUMITSU Nobuyoshi  筑波大学, 医学医療系, 准教授 (40277075)

Co-Investigator(Kenkyū-buntansha) 土谷 邦彦  国立研究開発法人日本原子力研究開発機構, 原子力科学研究部門 大洗研究開発センター 照射試験炉センター, 課長 (50343926)
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2015: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords99Mo / 99mTc / ジェネレータ / 国産化 / 99mTc / アルミナ / 吸着材 / 99mTc
Outline of Final Research Achievements

Mesoporous processing was performed on Mo adsorbent alumina. The firing temperature was gradually changed to 500 - 1200 degrees and mesoporous structure with many pores on the surface was confirmed with a scanning microscope. The specific surface area is 275 m 2 / g when baked at 600 ° C., the specific surface area is 230 m 2 / g at 700 ° C. and Mo adsorption amount was as high as 40 mg / g, which was about 3 times higher than that of the existing alumina which specific surface area is 110 m 2 / g and Mo adsorption amount is 10 - 20 mg / g,. On the other hand, at 900 ° C, the specific surface area was 139 m 2 / g, which is equivalent to that of existing alumina, and it became clear that the surface area and Mo adsorption ability greatly changed by changing the conditions such as firing temperature.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (2 results)

All 2016

All Journal Article (2 results) (of which Peer Reviewed: 2 results,  Open Access: 2 results)

  • [Journal Article] モリブデン-99/テクネチウム-99m(99Mo/99mTc)国産化と吸着剤の開発2016

    • Author(s)
      福光 延吉
    • Journal Title

      臨床核医学

      Volume: 49 Pages: 74-77

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access
  • [Journal Article] 研究用原子炉により99Mo/99mTc国産化を目指した99Mo/99mTcジェネレータ開発2016

    • Author(s)
      福光 延吉、土谷 邦彦、有賀 克彦、山内 悠輔
    • Journal Title

      Isotopenews

      Volume: 742 Pages: 20-24

    • Related Report
      2016 Annual Research Report 2015 Research-status Report
    • Peer Reviewed / Open Access

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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