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A novel parameter to evaluate thyroid function with dual-energy CT in patients with hyperthyroidism

Research Project

Project/Area Number 15K15450
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Radiation science
Research InstitutionGunma University

Principal Investigator

Otake Hidenori  群馬大学, 大学院医学系研究科, 研究員 (60727535)

Co-Investigator(Kenkyū-buntansha) 中島 崇仁  群馬大学, 大学院医学系研究科, 特任准教授 (70375559)
Research Collaborator Higuchi Tetsuya  群馬大学, 医学系研究科, 准教授
Tsushima Yoshito  群馬大学, 医学系研究科, 教授
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2016: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
KeywordsデュアルエナジーCT / DECT / 甲状腺機能亢進症 / 甲状腺シンチグラフィー / ヨード / 甲状腺 / デュアルエナジー / CT / ヨードマップ
Outline of Final Research Achievements

We employed dual-energy CT (DECT) to measure the concentration of iodine in thyroid gland. In patients with Graves' disease, the correlation between iodine concentrations (ICs) measured by DECT and CT values were evaluated and then ICs were examined for the correlation to iodine uptake ratios (IURs) by thyroid scintigraphy. Moderate correlation was seen in the comparison with ICs and CT values. However, it was lower than the result expected from phantom study. IURs at 3h had moderate correlation to ICs. In conclusion, ICs measured by DECT may predict thyroid function in patients with hyperthyroidism.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (1 results)

All 2017

All Presentation (1 results) (of which Int'l Joint Research: 1 results)

  • [Presentation] A novel parameter to evaluate thyroid function with dual-energy CT in patients with hyperthyroidism,2017

    • Author(s)
      Nakajima T, Otake H, Binh DD, Higuchi T, Tsushima Y.
    • Organizer
      European congress of radiology
    • Place of Presentation
      Vienna, Austria
    • Year and Date
      2017-03-01
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research

URL: 

Published: 2015-04-16   Modified: 2018-03-22  

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