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Development of a pulsatile simulator fir quantitatively assess procedural outcomes of stent grafts for thoracic artery aneurysm

Research Project

Project/Area Number 15K15512
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Cardiovascular surgery
Research InstitutionWaseda University

Principal Investigator

Iwasaki Kiyotaka  早稲田大学, 理工学術院, 教授(任期付) (20339691)

Co-Investigator(Kenkyū-buntansha) 植松 美幸  国立医薬品食品衛生研究所, 医療機器部, 主任研究官 (10424813)
山崎 健二  東京女子医科大学, 医学部, 教授 (30241087)
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2016: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2015: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
Keywords生体のモデル化 / 実験シミュレーション / 治療技術の高度化 / 生体代替評価システム / 非臨床評価 / 大動脈瘤 / ステントグラフト / 拍動循環シミュレータ / 非臨床評価法 / 治療技術 / トレーニング / 評価科学 / in vitro
Outline of Final Research Achievements

In this study, we developed the novel pulsatile circulatory system where doctors could perform whole procedure of stent graft deployment for sealing thoracic aneurysm under a clinically-relevant pulsatile flow. The Elastic 3D thoracic artery with aneurysm, abdominal, femoral artery were replicated from CT data of patients and incorporated into pulsatile flow system. The patient-specific pulsatile flow system was effective to quantitatively assess factors influencing on the interventional procedure. The method developed here would be useful for improving interventional skill.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2017 2016

All Presentation (4 results) (of which Int'l Joint Research: 2 results)

  • [Presentation] Chimney technique を用いた腹部ステントグラフト治療におけるステントグラフトシーリング長とエンドリーク量との相関2017

    • Author(s)
      宿澤孝太,赤岡拓、藤井智也、伊藤大輝,梅津先生-、大木隆雄,岩﨑清隆
    • Organizer
      日本機械学会第29回バイオエンジニアリング講演会
    • Place of Presentation
      愛知
    • Year and Date
      2017-01-20
    • Related Report
      2016 Annual Research Report
  • [Presentation] Investigation of factors influencing the rotation of fenestrated stent-graft in deployment process using a pulsatile circulatory simulator2016

    • Author(s)
      H.Ito,A.Takahashi,T.Azuma,Y.Yokoi,M.Uematsu,M.Umezu,K.Iwasak
    • Organizer
      The 16th International Conference on Biomedical Engineering
    • Place of Presentation
      Singapore
    • Year and Date
      2016-12-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of a quantification method of three-dimensional aortic arch shape with aneurysm for exploring factors inducing endoleak2016

    • Author(s)
      T.Fujii, A Takahashi, T Azuma, Y Yokoi, M Uematsu, M Umezu, K.Iwasaki
    • Organizer
      The 16th International Conference on Biomedical Engineering
    • Place of Presentation
      Singapore
    • Year and Date
      2016-12-10
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] エンドリークの要因解明に向けた瘤を有する弓部大動脈形状の定量化手法の構築2016

    • Author(s)
      藤井智也,岩﨑清隆,高橋東,東隆,横井良彦,伊藤大輝,植松美幸,梅津光生
    • Organizer
      第27回バイオフロンティア講演会
    • Place of Presentation
      札幌
    • Year and Date
      2016-10-23
    • Related Report
      2016 Annual Research Report

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Published: 2015-04-16   Modified: 2018-03-22  

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