| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2017: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Outline of Final Research Achievements |
Muscle, a power source in our musculoskeletal function, has long been studied in medicine and biology for its regeneration mechanism by tissue stem cells and transcriptional control system starting with MyoD. We identified Rp 58 as a transcription factor essential for muscle differentiation and showed that this could be responsible for muscle differentiation control in conjunction with DNA methylation. The results of this research are expected to contribute to muscle diseases and regenerative medicine.
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