| Project/Area Number |
15K15559
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Orthopaedic surgery
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| Research Institution | National Center for Child Health and Development |
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Principal Investigator |
TAKAYAMA SHINICHIRO 国立研究開発法人国立成育医療研究センター, 臓器・運動器病態外科部, 部長 (40138045)
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| Co-Investigator(Kenkyū-buntansha) |
梅澤 明弘 国立研究開発法人国立成育医療研究センター, 再生医療センター, 副所長/再生医療センター長 (70213486)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Project Status |
Completed (Fiscal Year 2017)
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| Budget Amount *help |
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2016: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2015: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
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| Keywords | 小児運動器学 / キメラタンパク質 / 再生医療 / 生分解性材料 |
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| Outline of Final Research Achievements |
By using mesenchymal cells, regenerative induction therapy that activates functions related to target tissues is considered to be one of regenerative medicine. Mesenchymal cells have both high proliferative ability, self-replicating ability and partial totipotency properties, and are also attracting attention as a transplantation device for cell replacement therapy. Bone disease can occur to anyone in daily life. In this study, a basic experiment as a scaffold material using a recombinant protein was carried out and verification of its effectiveness was completed.
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