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Visualization of swallowing mechanics by 4D-computer graphics and its application to treatment of dysphagia

Research Project

Project/Area Number 15K15620
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Otorhinolaryngology
Research InstitutionKochi University

Principal Investigator

HYODO Masamitsu  高知大学, 教育研究部医療学系臨床医学部門, 教授 (00181123)

Co-Investigator(Kenkyū-buntansha) 道脇 幸博  昭和大学, 歯学部, 兼任講師 (40157540)
越塚 誠一  東京大学, 大学院工学系研究科(工学部), 教授 (80186668)
Research Collaborator KIKUCHI Takahiro  武蔵野赤十字病院
HIROSE Kahori  高知大学, 教育研究部
NAGAO Asuka  高知大学, 教育研究部
NAKAHIRA Maya  高知大学, 医学部附属病院リハビリテーション部
Project Period (FY) 2015-04-01 – 2017-03-31
Project Status Completed (Fiscal Year 2016)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Keywordsコンピューター・グラフィクス / 4次元CG / 嚥下運動の可視化 / 高解像度マノメトリー / コンピューターグラフィクス / 3D-CT / 4次元画像 / 嚥下内視鏡検査 / 嚥下造影検査 / 嚥下機能
Outline of Final Research Achievements

In this study, we created 3D images of swallowing organs including the mandible, tongue, pharynx, and larynx based on the data by multi-row detector type CT. Based on this, computer graphics (CG) was made to visualize movement of the pharynx and larynx during swallowing as a 4D image. Then, by transferring the bolus as an aggregate of particles from the oral cavity to the pharynx, we could observe the movements of the swallowing organ and the bolus from an arbitrary direction.
Next, we created CG on an elderly patient showing aspiration. The position of the larynx was lower than that of healthy subjects. And, laryngeal elevation during swallowing, epiglottic flexion disturbance, and aspiration of the bolus was confirmed. By transferring the bolus from the oral cavity to the pharynx, it was possible to visualize the timing of aspiration and the mismatch between the movements of the swallowing organs and the bolus.

Report

(3 results)
  • 2016 Annual Research Report   Final Research Report ( PDF )
  • 2015 Research-status Report
  • Research Products

    (45 results)

All 2017 2016 2015

All Journal Article (12 results) (of which Int'l Joint Research: 1 results,  Peer Reviewed: 4 results,  Open Access: 1 results) Presentation (28 results) (of which Int'l Joint Research: 4 results,  Invited: 12 results) Book (5 results)

  • [Journal Article] 抗加齢ドックからみた嚥下障害のリスク因子2017

    • Author(s)
      三瀬和代、白馬信洋、兵頭政光
    • Journal Title

      嚥下医学

      Volume: 6 Pages: 22-28

    • Related Report
      2016 Annual Research Report
  • [Journal Article] Numerical simulation of interaction between organs and food bolus during swallowing and aspiration2017

    • Author(s)
      Kikuchi T, Michiwaki Y, Koshizuka S, Kamiya T, Toyama Y, Tamai T
    • Journal Title

      Comput Biol Med

      Volume: 80 Pages: 114-123

    • DOI

      10.1016/j.compbiomed.2016.11.017

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Determination of the cut-off score of an endoscopic scoring method to predict whether elderly patients with dysphagia can eat pureed diets.2016

    • Author(s)
      Sakamoto T, Horiuchi A, Makino T, Kajiyama M, Tanaka N, Hyodo M
    • Journal Title

      World J Gastrointest Endosc

      Volume: 8 Issue: 6 Pages: 288-294

    • DOI

      10.4253/wjge.v8.i6.288

    • Related Report
      2016 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Ginger Orally Disintegrating Tablets to Improve Swallowing in Older People2016

    • Author(s)
      Hirata A, Funato H, Nakai M, Iizuka M, Abe N, Yagi Y, Shiraishi H, Jobu K, Yokota J, Hirose K, Hyodo M, Miyamura M.
    • Journal Title

      Biological and Pharmaceutical Bulletin

      Volume: 39 Issue: 7 Pages: 1107-1111

    • DOI

      10.1248/bpb.b15-01045

    • NAID

      130005160768

    • ISSN
      0918-6158, 1347-5215
    • Related Report
      2016 Annual Research Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] 嚥下障害の外科的アプローチ -嚥下機能改善手術-2016

    • Author(s)
      兵頭政光
    • Journal Title

      耳鼻咽喉科・頭頸部外科

      Volume: 88 Pages: 300-303

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 高齢者の摂食嚥下機能と特殊性2016

    • Author(s)
      兵頭政光
    • Journal Title

      MB ENT

      Volume: 196 Pages: 1-4

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 嚥下機能改善手術症例の臨床的検討2016

    • Author(s)
      長尾明日香、田中加緒里、弘瀬かほり、小森正博、兵頭政光
    • Journal Title

      日本気管食道科学会会報

      Volume: 67 Pages: 398-405

    • NAID

      130006881033

    • Related Report
      2016 Annual Research Report
  • [Journal Article] 経口摂取判断のための嚥下機能検査2015

    • Author(s)
      兵頭政光
    • Journal Title

      MB ENT

      Volume: 179 Pages: 138-142

    • Related Report
      2015 Research-status Report
  • [Journal Article] 咀嚼と嚥下のメカニズム2015

    • Author(s)
      兵頭政光
    • Journal Title

      日医雑誌

      Volume: 144 Pages: 473-476

    • Related Report
      2015 Research-status Report
  • [Journal Article] 超細径・軽量経鼻内視鏡は嚥下機能検査に有用か2015

    • Author(s)
      兵頭政光
    • Journal Title

      日本医事新報

      Volume: 4767 Pages: 34-40

    • Related Report
      2015 Research-status Report
  • [Journal Article] Swallowing Function Improvement Effect of Ginger (Zingiber officinale)2015

    • Author(s)
      Abe N, Hirata A, Hyodo M, et al.
    • Journal Title

      Food Sci Tech Res

      Volume: 21 Pages: 705-714

    • NAID

      130005106157

    • Related Report
      2015 Research-status Report
    • Peer Reviewed
  • [Journal Article] 私の治療方針「羞明、眼瞼下垂および球症状を呈した75歳女性例」言語聴覚士の立場から2015

    • Author(s)
      中平真矢、兵頭政光
    • Journal Title

      嚥下医学

      Volume: 5 Pages: 17-18

    • Related Report
      2015 Research-status Report
  • [Presentation] 嚥下障害の病態評価と治療-耳鼻咽喉科の立場から-2017

    • Author(s)
      兵頭政光
    • Organizer
      第48回高知県リハビリテーション研究大会
    • Place of Presentation
      総合あんしんセンター(高知県高知市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 嚥下障害の病態評価と治療2017

    • Author(s)
      兵頭政光
    • Organizer
      高知中央・高幡・安芸医療圏脳卒中地域連携の会合同会合
    • Place of Presentation
      高知大学医学部附属病院(高知県南国市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 4D-CGによる嚥下運動の可視化2017

    • Author(s)
      兵頭政光、長尾明日香、道脇幸博
    • Organizer
      第9回高知工科大学&高知大学医工連帯交流会
    • Place of Presentation
      高知工科大学(高知県香美市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 嚥下機能の病態評価と嚥下障害への対応2016

    • Author(s)
      兵頭政光
    • Organizer
      日本臨床麻酔学会 第36回大会
    • Place of Presentation
      高知市文化プラザかるぽーと(高知県高知市)
    • Year and Date
      2016-11-03
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 術後経過から見た嚥下機能改善手術の適応と意義2016

    • Author(s)
      長尾明日香、中平真矢、兵頭政光
    • Organizer
      第22回日本摂食嚥下リハビリテーション学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 嚥下障害患者における舌骨上筋群の筋力増強訓練に関する筋電図学的検討2016

    • Author(s)
      中平真矢,室伏祐介,長尾明日香,永野靖典,兵頭政光
    • Organizer
      第22回日本摂食嚥下リハビリテーション学会学術大会
    • Place of Presentation
      朱鷺メッセ(新潟県新潟市)
    • Year and Date
      2016-09-23
    • Related Report
      2016 Annual Research Report
  • [Presentation] 口腔・咽頭・喉頭領域の画像診断2016

    • Author(s)
      兵頭政光
    • Organizer
      第29回日本口腔・咽頭科学会総会ならびに学術講演会
    • Place of Presentation
      松江テルサ(島根県松江市)
    • Year and Date
      2016-09-08
    • Related Report
      2016 Annual Research Report
  • [Presentation] Numerical simulation of interaction between of organs and food bolus: the effect of the laryngeal excursion2016

    • Author(s)
      Kikuchi T, Michiwaki Y, Koshizuka S, Kamiya T, Toyama Y, Wada T, Jinno N, Takai M, Hanyu K
    • Organizer
      4th International Workshop on Biomechanical and Parametric Modeling of Human Anatomy
    • Place of Presentation
      University of British Columbia(Vancouver, Canada)
    • Year and Date
      2016-08-26
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Simple and semi-quantitatine system for flexible endoscopic evaluation of seallowing and its clinical significance2016

    • Author(s)
      Hyodo M, Nagao A, Hirose K
    • Organizer
      30th World Congress of the International Association of Logopedics and Phoniatrics
    • Place of Presentation
      Citywest Hotel Conference & Event Centre(Dublin, Ireland)
    • Year and Date
      2016-08-21
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] Development of 3D swallowing simulator Swallow Vision(TM); to visualize the changes of the physical values and the pathline of the food bolus flow during swallowing2016

    • Author(s)
      Hanyu K, Kamiya T, Toyama Y, Takai M, Kikuchi T, Michiwaki Y
    • Organizer
      4th International Conference on Food Oral Processing
    • Place of Presentation
      SwissTech Convention Center(Lausanne, Switzerland)
    • Year and Date
      2016-07-03
    • Related Report
      2016 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 咽頭・喉頭の機能とその評価2016

    • Author(s)
      兵頭政光
    • Organizer
      第53回日本リハビリテーション医学会学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-06-09
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 嚥下障害の病態評価と治療 -耳鼻咽喉科医の役割-2016

    • Author(s)
      兵頭政光
    • Organizer
      第55回宮崎県耳鼻咽喉科懇話会のご案内
    • Place of Presentation
      宮崎観光ホテル, 宮崎市
    • Year and Date
      2016-03-10
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 症例から学ぶ喉頭・気管疾患および嚥下障害への対応2016

    • Author(s)
      兵頭政光
    • Organizer
      第22回秋田上気道疾患研究会
    • Place of Presentation
      ホテルメトロポリタン秋田, 秋田市
    • Year and Date
      2016-03-05
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 高解像度マノメトリーを用いた嚥下リハビリテーション効果の検討2016

    • Author(s)
      長尾明日香,弘瀬かほり,兵頭政光
    • Organizer
      第28回日本喉頭科学会総会・学術講演会
    • Place of Presentation
      コングレコンベンションセンター, 大阪市
    • Year and Date
      2016-03-04
    • Related Report
      2015 Research-status Report
  • [Presentation] 嚥下機能改善手術2016

    • Author(s)
      兵頭政光
    • Organizer
      第64回愛知県耳鼻咽喉科手術手技懇話会
    • Place of Presentation
      名鉄ニューグランドホテル, 名古屋市
    • Year and Date
      2016-02-18
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 舌骨上筋群に対する筋力増強訓練における筋電図学的検討2016

    • Author(s)
      中平真矢,室伏祐介,兵頭政光, 他
    • Organizer
      第39回日本嚥下医学会総会・学術講演会
    • Place of Presentation
      大阪国際交流センター, 大阪市
    • Year and Date
      2016-02-12
    • Related Report
      2015 Research-status Report
  • [Presentation] 頭頸部癌治療にともなう嚥下障害への対応2016

    • Author(s)
      兵頭政光
    • Organizer
      第4回西日本中部地区頭頸部腫瘍研究会
    • Place of Presentation
      岡山県医師会館(岡山県岡山市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 嚥下障害の病態診断と治療~耳鼻咽喉科の立場から~2016

    • Author(s)
      兵頭政光
    • Organizer
      第25回長野県胃ろう研究会
    • Place of Presentation
      総合社会福祉センター(長野県松本市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 嚥下障害の病態診断と治療~耳鼻咽喉科の立場から~2016

    • Author(s)
      兵頭政光
    • Organizer
      高知県口のリハビリテーション研究会
    • Place of Presentation
      総合あんしんセンター(高知県高知市)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 診療ガイドラインからみた嚥下障害への対応2016

    • Author(s)
      兵頭政光
    • Organizer
      第128回沖縄県地方部会総会、学術講演会・講習会
    • Place of Presentation
      琉球大学医学部(沖縄県西原町)
    • Related Report
      2016 Annual Research Report
    • Invited
  • [Presentation] 高解像度マノメトリーによる嚥下機能の客観的・定量的評価と治療への応用2016

    • Author(s)
      長尾明日香、兵頭政光
    • Organizer
      第8回高知工科大学&高知大学医工連帯交流会
    • Place of Presentation
      高知大学医学部(高知県南国市)
    • Related Report
      2016 Annual Research Report
  • [Presentation] 当科における嚥下機能改善手術症例の臨床的検討2015

    • Author(s)
      長尾明日香,弘瀬かほり,小林泰輔,兵頭政光,横畠悦子
    • Organizer
      日本耳鼻咽喉科学会第41回四国四県地方部会連合学会
    • Place of Presentation
      愛媛県医師会館, 松山市
    • Year and Date
      2015-12-06
    • Related Report
      2015 Research-status Report
  • [Presentation] Simple and semi-quantitative scoring system for flexible endoscopic evaluation of swallowing and its clinical significance2015

    • Author(s)
      Hyodo M
    • Organizer
      13th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
    • Place of Presentation
      Hitotsubashi Hall, National Center of Sciences, Tokyo
    • Year and Date
      2015-12-03
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 診療ガイドラインからみた嚥下障害への対応2015

    • Author(s)
      兵頭政光
    • Organizer
      第45回南大阪耳鼻咽喉科研究会
    • Place of Presentation
      ホテル日航大阪, 大阪市
    • Year and Date
      2015-11-14
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 頭頸部癌術後の摂食嚥下障害に対する摂食嚥下リハビリテーションの検討2015

    • Author(s)
      高橋朝妃,長尾明日香,弘瀬かほり,兵頭政光
    • Organizer
      第60回日本音声言語医学会総会・学術講演会
    • Place of Presentation
      ウインクあいち, 名古屋市
    • Year and Date
      2015-10-15
    • Related Report
      2015 Research-status Report
  • [Presentation] 嚥下内視鏡検査の実際と評価法2015

    • Author(s)
      兵頭政光
    • Organizer
      第18回広島県耳鼻咽喉科研修会
    • Place of Presentation
      ホテルグランヴィア広島, 広島市
    • Year and Date
      2015-09-12
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 嚥下障害症例の経口摂取の有無における嚥下内視鏡検査スコア評価法の有用性2015

    • Author(s)
      山川泰幸,弘瀬かほり,兵頭政光
    • Organizer
      第28回日本口腔・咽頭科学会総会ならびに学術講演会
    • Place of Presentation
      ホテル阪神, 大阪市
    • Year and Date
      2015-09-10
    • Related Report
      2015 Research-status Report
  • [Presentation] 嚥下内視鏡検査の実際とその評価法2015

    • Author(s)
      兵頭政光
    • Organizer
      第15回愛媛県摂食嚥下研究会
    • Place of Presentation
      愛媛県立県民文化会館, 松山市
    • Year and Date
      2015-05-10
    • Related Report
      2015 Research-status Report
  • [Book] 今日の治療指針20172017

    • Author(s)
      兵頭政光
    • Total Pages
      2096
    • Publisher
      医学書院
    • Related Report
      2016 Annual Research Report
  • [Book] 耳鼻咽喉科・頭頸部外科 研修ノート2016

    • Author(s)
      兵頭政光
    • Total Pages
      672
    • Publisher
      診断と治療社
    • Related Report
      2016 Annual Research Report
  • [Book] EBM 耳鼻咽喉科・頭頸部外科の治療2015-2016 edition2015

    • Author(s)
      兵頭政光
    • Total Pages
      688
    • Publisher
      中外医学社
    • Related Report
      2015 Research-status Report
  • [Book] 今日の診断指針 第7版2015

    • Author(s)
      兵頭政光
    • Total Pages
      2103
    • Publisher
      医学書院
    • Related Report
      2015 Research-status Report
  • [Book] 口腔咽頭の臨床 第3版2015

    • Author(s)
      兵頭政光
    • Total Pages
      203
    • Publisher
      医学書院
    • Related Report
      2015 Research-status Report

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Published: 2015-04-16   Modified: 2018-03-22  

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