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Regenerating lamina cribrosa as a novel treatment for glaucoma

Research Project

Project/Area Number 15K15629
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Ophthalmology
Research InstitutionTokyo Medical and Dental University

Principal Investigator

OHNO-MATSUI Kyoko  東京医科歯科大学, 大学院医歯学総合研究科, 教授 (30262174)

Co-Investigator(Kenkyū-buntansha) 相原 一  東京大学, 医学部附属病院, 准教授 (80222462)
吉田 武史  東京医科歯科大学, 医学部附属病院, 助教 (30451941)
諸星 計  東京医科歯科大学, 医学部, 非常勤講師 (60598415)
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2015: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords眼発生 / 再生医学 / 病的近視 / 緑内障 / 眼発生・再生医学
Outline of Final Research Achievements

Human fibroblasts were cultured and were injected around the retrobulbar optic nerve in rats. Sudden death after injection was seen and this was considered to be caused by migration of injected cells into cerebrospinal fluid. Thus, we the injected human fibrioblasts along the scleral surface but somewhat distant from the optic nerve. By this methods, sudden death was avoided. One week after injection, transplanted cells proliferated and migrated along the peripapillary sclera. Two weeks after injection, transplanted cells disappeared however produced collagen remained and the peripapillary sclera was thickened. However, no animals exhibited the migration of transplanted fibroblasts toward inside of the optic nerve.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (80 results)

All 2017 2016 2015

All Journal Article (22 results) (of which Int'l Joint Research: 17 results,  Peer Reviewed: 20 results,  Acknowledgement Compliant: 16 results,  Open Access: 3 results) Presentation (55 results) (of which Int'l Joint Research: 36 results,  Invited: 46 results) Book (3 results)

  • [Journal Article] Intraocular Pressure and Glaucomatous Optic Neuropathy in High Myopia2017

    • Author(s)
      Jonas Jost B.、Nagaoka Natsuko、Fang Yu Xin、Weber Pascal、Ohno-Matsui Kyoko
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 58 Issue: 13 Pages: 5897-5897

    • DOI

      10.1167/iovs.17-21942

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Potential role of sirtuin 1 in M?ller glial cells in mice choroidal neovascularization2017

    • Author(s)
      Ishida Tomoka、Yoshida Takeshi、Shinohara Kosei、Cao Kejia、Nakahama Ken-ichi、Morita Ikuo、Ohno-Matsui Kyoko
    • Journal Title

      PLOS ONE

      Volume: 12 Issue: 9 Pages: e0183775-e0183775

    • DOI

      10.1371/journal.pone.0183775

    • Related Report
      2017 Annual Research Report
  • [Journal Article] Optical Coherence Tomographic Imaging of Posterior Episclera and Tenon's Capsule2017

    • Author(s)
      Ohno-Matsui Kyoko、Fang Yuxin、Morohoshi Kei、Jonas Jost B.
    • Journal Title

      Investigative Opthalmology & Visual Science

      Volume: 58 Issue: 9 Pages: 3389-3389

    • DOI

      10.1167/iovs.16-21394

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Establishment of novel therapy to reduce progression of myopia in rats with experimental myopia by fibroblast transplantation on sclera.2017

    • Author(s)
      Shinohara K, Yoshida T, Liu H, Ichinose S, Ishida T, Nakahama K, Nagaoka N, Moriyama M, Morita I, Ohno-Matsui K.
    • Journal Title

      Journal of Tissue Engineering and Regenerative Medicine

      Volume: 印刷中 Issue: 1 Pages: e451-e461

    • DOI

      10.1002/term.2275

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Glaucoma in high myopia and parapapillary delta zone.2017

    • Author(s)
      Jonas JB, Weber P, Nagaoka N, Ohno-Matsui K.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 4 Pages: e0175120-e0175120

    • DOI

      10.1371/journal.pone.0175120

    • Related Report
      2017 Annual Research Report 2016 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Parapapillary gamma and delta zone in high myopia.2017

    • Author(s)
      Jonas JB, Fang Y, Weber P, Ohno-Matsui K.
    • Journal Title

      Retina

      Volume: 印刷中 Issue: 5 Pages: 931-938

    • DOI

      10.1097/iae.0000000000001650

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Brunch Membrane and the mechanism of myopization:a new theory.2017

    • Author(s)
      Jonas JB, Ohno-Matsui K, Jiang WJ, Panda-Jonas S.
    • Journal Title

      Retina

      Volume: 印刷中 Issue: 8 Pages: 1428-1440

    • DOI

      10.1097/iae.0000000000001464

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Parapapillary Diffuse Choroidal Atrophy in Children is Associated with Extreme Thinning of Parapapillary Choroid.2017

    • Author(s)
      Yokoi T, Zhu D, Bi HS, Jonas JB, Jonas RA, Nagaoka N, Moriyama M, Yoshida T, Ohno-Matsui K.
    • Journal Title

      Investigative Ophthalmology & Visual Science

      Volume: 58 Issue: 2 Pages: 901-906

    • DOI

      10.1167/iovs.16-20652

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Retinal pigment epithelium cell density in relationship to axial length in human eyes.2017

    • Author(s)
      Jonas JB, Ohno-Matsui K, Holbach L, Panda-Jonas S.
    • Journal Title

      Acta Ophthalmologica

      Volume: 95 Issue: 1

    • DOI

      10.1111/aos.13188

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Optic nerve head histopathology in high axial myopia.2017

    • Author(s)
      Jonas JB, Ohno-Matsui K, Panda-Jonas S.
    • Journal Title

      Journal of Glaucoma

      Volume: 26 Issue: 2 Pages: 187-193

    • DOI

      10.1097/ijg.0000000000000574

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Peripapillary diffuse chorioretinal atrophy in children as a sign of eventual pathologic myopia in adults.2016

    • Author(s)
      Yokoi T, Jonas JB, Shimada N, Nagaoka N, Moriyama M, Yoshida T, Ohno-Matsui K.
    • Journal Title

      Ophthalmology

      Volume: 123 Issue: 8 Pages: 1783-1787

    • DOI

      10.1016/j.ophtha.2016.04.029

    • Related Report
      2016 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Peripapillary Arterial Ring of Zinn-Haller in Highly Myopic Eyes As Detected by Optical Coherence Tomography Angiography.2016

    • Author(s)
      Ishida T, Jonas JB, Ishii M, Shinohara K, Ikegaya Y, Ohno-Matsui K.
    • Journal Title

      Retina

      Volume: 印刷中

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Features of posterior staphylomas analyzed in wide-field fundus images in patients with unilateral and bilateral pathologic myopia.2016

    • Author(s)
      Ohno-Matsui K, Alkabes M, Salinas C, Mateo C, Moriyama M, Cao K, Yoshida T.
    • Journal Title

      Retina

      Volume: 印刷中

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Macular Bruch's membrane holes in choroidal neovascularization-related myopic macular atrophy by swept-source optical coherence tomography.2016

    • Author(s)
      Ohno-Matsui K, Jonas JB, Spaide RF.
    • Journal Title

      American Journal of Ophthalmology

      Volume: 162 Pages: 133-139

    • DOI

      10.1016/j.ajo.2016.03.019

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Glaucomatous-Type Optic Discs in High Myopia.2015

    • Author(s)
      Nagaoka N, Jonas JB, Morohoshi K, Moriyama M, Shimada N, Yoshida T, Ohno-Matsui K.
    • Journal Title

      PLoS One.

      Volume: 10 Issue: 10 Pages: 362-368

    • DOI

      10.1371/journal.pone.0138825

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access / Int'l Joint Research
  • [Journal Article] Current and predicted demographics of high myopia and an update of its associated pathological changes.2015

    • Author(s)
      Verkicharla PK, Ohno-Matsui K, Saw SM.
    • Journal Title

      Ophthalmic and Physiological Optics

      Volume: 35 Issue: 5 Pages: 465-475

    • DOI

      10.1111/opo.12238

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Chorioretinal folds in eyes with myopic staphyloma.2015

    • Author(s)
      Ishida T, Shinohara K, Tanaka Y, Moriyama M, Morohoshi K, Shimada N, Yoshida T, Ohno-Matsui K.
    • Journal Title

      Am J Ophthalmol.

      Volume: 160 Issue: 3 Pages: 608-613

    • DOI

      10.1016/j.ajo.2015.05.028

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research
  • [Journal Article] Comparison of clinical features in highly myopic eyes with and without dome-shaped macula Ophthalmology.2015

    • Author(s)
      Liang IC, Shimada N, Tanaka Y, Nagaoka N, Moriyama M, Yoshida T, Ohno-Matsui K.
    • Journal Title

      Ophthalmology

      Volume: 122 Issue: 8 Pages: 1591-1600

    • DOI

      10.1016/j.ophtha.2015.04.012

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Association between the CDKN2B-AS1 gene and primary open angle glaucoma with high myopia in Japanese patients.2015

    • Author(s)
      Kimura Y, Akagi T, Miyake M, Yamashiro K, Yoshikawa M, Yamada H, Hasegawa T, Suda K, Nakanishi H, Ohashi-Ikeda H, Gotoh N, Hangai M, Moriyama M, Ohno-Matsui K, Yoshimura N.
    • Journal Title

      Ophthalmic Genetics

      Volume: 2 Issue: 2 Pages: 1-3

    • DOI

      10.3109/13816810.2015.1020559

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Journal Article] Identification of myopia-associated WNT7B polymorphisms provides insights into the mechanism underlying the development of myopia.2015

    • Author(s)
      Miyake M, Yamashiro K, Tabara Y, Suda K, Morooka S, Nakanishi H, Khor CC, Chen P, Qiao F, Nakata I, Akagi-Kurashige Y, Gotoh N, Tsujikawa A, Meguro A, Kusuhara S, Polasek O, Hayward C, Wright AF, Campbell H, Mizuki N, et al
    • Journal Title

      Nat Commun

      Volume: 印刷中 Issue: 1 Pages: 6689-6689

    • DOI

      10.1038/ncomms7689

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Open Access
  • [Journal Article] International photographic classification and grading system for myopic maculopathy.2015

    • Author(s)
      Ohno-Matsui K, Kawasaki R, Jonas JB, Cheung CMG, Saw SM, Verhoeven VJ, Klaver CC, Moriyama M, Shinohara K, Kawasaki Y, Yamazaki M, Meuer S, Ishibashi T, Yasuda M, Yamashita H, Sugano A, Wang JJ, Mitchell P, Wong TY, for the META-analysis for Pathologic Myopia (META-PM) Study Group.
    • Journal Title

      American Journal of Ophthalmology

      Volume: 159 Issue: 5 Pages: 877-883

    • DOI

      10.1016/j.ajo.2015.01.022

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Int'l Joint Research / Acknowledgement Compliant
  • [Journal Article] Extreme thinning or loss of inner neural retina along the staphyloma edge in eyes with pathologic myopia.2015

    • Author(s)
      Tanaka Y, Shimada N, Ohno-Matsui K.
    • Journal Title

      American Journal of Ophthalmology

      Volume: 159 Issue: 4 Pages: 677-682

    • DOI

      10.1016/j.ajo.2015.01.004

    • Related Report
      2015 Research-status Report
    • Peer Reviewed / Acknowledgement Compliant
  • [Presentation] The impact of pathologic myopia on visual impairment in asia and beyond.2017

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2017 Asia-Pacific Academy of Ophthalmology
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2017-03-04
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Cutting edge of pathologic myopia2017

    • Author(s)
      Ohno-Matsui K, Cheung G, Lai T, Hirakata A
    • Organizer
      American Academy of Ophthalmology
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] New imaging findings in pathologic myopia2017

    • Author(s)
      Ohno-Matsui K
    • Organizer
      American Academy of Ophthalmology
    • Related Report
      2017 Annual Research Report
    • Invited
  • [Presentation] Ultra-widefield OCT method to advance the visualization of posterior staphylomas and accompanying vitreoretinal changes in pathologic myopia2017

    • Author(s)
      Ohno-Matsui K, Shinohara K
    • Organizer
      The Retina Society
    • Related Report
      2017 Annual Research Report
    • Int'l Joint Research
  • [Presentation] 病的近視における失明原因の解明.2016

    • Author(s)
      須賀 洸希、森山 無価、 長岡 奈都子、大野京子.
    • Organizer
      第70回日本臨床眼科学会
    • Place of Presentation
      国立京都国際会館・グランドプリンスホテル京都(京都府京都市)
    • Year and Date
      2016-11-06
    • Related Report
      2016 Research-status Report
  • [Presentation] Diagnosis and Management of Complications due to Pathologic Myopia.2016

    • Author(s)
      Ohno-Matsui K, Cheung G, Lai T, Hirakata A.
    • Organizer
      American Academy of Ophthalmology 2016
    • Place of Presentation
      Chicago (USA)
    • Year and Date
      2016-10-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] New Approaches to the Prevention and Treatment of Myopia.2016

    • Author(s)
      Grzybowski A, Repka MX, Koffler BH, Ohno-Matsui K, Trier K, Morgan I, Tan D.
    • Organizer
      American Academy of Ophthalmology 2016
    • Place of Presentation
      Chicago (USA)
    • Year and Date
      2016-10-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Spectral Domain and Swept Source OCT in the Diagnosis and Management of Vitreoretinal and Uveitic Disorders.2016

    • Author(s)
      Stanga P, Moussa MS, Ohno-Matsui K, Sadda SR.
    • Organizer
      American Academy of Ophthalmology 2016
    • Place of Presentation
      Chicago (USA)
    • Year and Date
      2016-10-17
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research
  • [Presentation] Imaging of Pathologic Myopia.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      3rd International conference on Pathologic Myopia
    • Place of Presentation
      ホテルニューオータニ(東京都千代田区)
    • Year and Date
      2016-10-01
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Diagnosis of pathlogic myopia and over view.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      3rd International conference on Pathologic Myopia
    • Place of Presentation
      ホテルニューオータニ(東京都千代田区)
    • Year and Date
      2016-09-30
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Imaging of optic nerve in highly myopic eyes.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      XXII International society for Eye Research Biennial Meeting
    • Place of Presentation
      京王プラザホテル(東京都新宿区)
    • Year and Date
      2016-09-27
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Swept-source OCT in pathologic myopia.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2016 APAO(Asia-Pacific Academy of Ophthalmology)
    • Place of Presentation
      Taiwan (China)
    • Year and Date
      2016-03-25
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Bruch’s membrane and pathologic myopia.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2016 APAO(Asia-Pacific Academy of Ophthalmology)
    • Place of Presentation
      Taiwan (China)
    • Year and Date
      2016-03-25
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Bruch membrane and myopic maculopathy.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2016 APAO(Asia-Pacific Academy of Ophthalmology)
    • Place of Presentation
      Taiwan (China)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Pathologic Myopia and its complications.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2016 APAO(Asia-Pacific Academy of Ophthalmology)
    • Place of Presentation
      Taiwan (China)
    • Year and Date
      2016-03-24
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Analyses of the Presence and Types of Posterior Staphyloma Using Wide-Field Imaging.2016

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      Fourth Annual International Retinal Imaging Symposium.
    • Place of Presentation
      Los Angeles (USA)
    • Year and Date
      2016-03-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Examinations of intrasclerally located Zinn-Haller ring by OCT angiography.2016

    • Author(s)
      Ohno-Matsui K, Ishida T.
    • Organizer
      39th Annual Macula Society Meeting.
    • Place of Presentation
      Miami (USA)
    • Year and Date
      2016-02-24
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] OCT angiography for choroidal neovascularization due to pathologic myopia.2016

    • Author(s)
      Ohno-Matsui K, Ishida T.
    • Organizer
      39th Annual Macula Society Meeting.
    • Place of Presentation
      Miami (USA)
    • Year and Date
      2016-02-23
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 病的近視による眼合併症の診断と治療.2016

    • Author(s)
      大野京子.
    • Organizer
      第2回TMDU眼科診療連携の会
    • Place of Presentation
      東京
    • Year and Date
      2016-01-21
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視の重要性.2016

    • Author(s)
      大野京子.
    • Organizer
      第1回近視研究会
    • Place of Presentation
      信濃町、東京
    • Year and Date
      2016-01-16
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 外傷性に両眼の黄斑ピット症候群類似病態を示した1例.2016

    • Author(s)
      大西由花、島田典明、横井多恵、大野京子.
    • Organizer
      12th Tokyo Glaucoma Retina Joint Conference
    • Place of Presentation
      六本木、東京
    • Year and Date
      2016-01-15
    • Related Report
      2015 Research-status Report
  • [Presentation] 病的近視診療の最前線.2015

    • Author(s)
      大野京子.
    • Organizer
      第19回奈良県黄斑疾患研究会
    • Place of Presentation
      奈良
    • Year and Date
      2015-11-19
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Spectral domain and swept source OCT in the diagnosis and management of vitreoretinal and uveitic disorders.2015

    • Author(s)
      Stanga P, Mussa M, Spaide RF, Ohno-Matsui K.
    • Organizer
      AAO(American Academy of Ophthalmology) 2015.
    • Place of Presentation
      Las Vegas (USA)
    • Year and Date
      2015-11-16
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Swept-Source OCT.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      AAO(American Academy of Ophthalmology) 2015.
    • Place of Presentation
      Las Vegas (USA)
    • Year and Date
      2015-11-14
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 病的近視診療の最前線.2015

    • Author(s)
      大野京子.
    • Organizer
      第5回関西眼科フォーラム
    • Place of Presentation
      大阪
    • Year and Date
      2015-11-01
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視診療の最前線.2015

    • Author(s)
      大野京子.
    • Organizer
      第17回教育フォーラム
    • Place of Presentation
      福岡
    • Year and Date
      2015-10-31
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視の目の神秘を探る旅へ.2015

    • Author(s)
      大野京子.
    • Organizer
      第69回日本臨床眼科学会ランチョンセミナー、第11回強度近視眼底研究会
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-23
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] より深くより鮮明に:Swept Source OCTの新しい可能性を探る.2015

    • Author(s)
      大野京子.
    • Organizer
      第69回日本臨床眼科学会モーニングセミナー
    • Place of Presentation
      名古屋
    • Year and Date
      2015-10-23
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Pathology of high myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      European Association for Vision and Eye Research(EVER)2015.
    • Place of Presentation
      Nice (France)
    • Year and Date
      2015-10-09
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Myopia-associated changes of the optic disc.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      European Association for Vision and Eye Research(EVER)2015.
    • Place of Presentation
      Nice (France)
    • Year and Date
      2015-10-08
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 病的近視診療の最前線.2015

    • Author(s)
      大野京子.
    • Organizer
      第186回埼京眼科学術集会
    • Place of Presentation
      川越
    • Year and Date
      2015-10-03
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視による脈絡膜新生血管(近視性CNV)の診断と治療.2015

    • Author(s)
      大野京子.
    • Organizer
      第51回日本眼光学学会総会
    • Place of Presentation
      岡山
    • Year and Date
      2015-09-27
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視診療の最新トピックス.2015

    • Author(s)
      大野京子.
    • Organizer
      平成27年度近畿ブロック夏期講習会
    • Place of Presentation
      奈良
    • Year and Date
      2015-08-30
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Imaging of pathologic myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      The 9th Congress of Asia-Pacific Vitreo-retina Society(APVRS).
    • Place of Presentation
      Sydney (Austlaria)
    • Year and Date
      2015-08-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Identifying prognostic factors for visual outcomes in patients with choroidal neovascularization secondary to pathological myopia: findings from the MIRROR study.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      The 9th Congress of Asia-Pacific Vitreo-retina Society(APVRS).
    • Place of Presentation
      Sydney (Austlaria)
    • Year and Date
      2015-08-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] 病的近視の脈絡膜新生血管に対する診断と治療.2015

    • Author(s)
      大野京子.
    • Organizer
      千葉臨床眼科フォーラム
    • Place of Presentation
      幕張
    • Year and Date
      2015-07-18
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視の今昔:治らない変性疾患から治療、そして予防できる疾患へ.2015

    • Author(s)
      大野京子.
    • Organizer
      第6回千代田眼科夏のフォーラム
    • Place of Presentation
      日本橋、東京
    • Year and Date
      2015-07-10
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視診療の進歩.2015

    • Author(s)
      大野京子.
    • Organizer
      第30回とやま眼科学術講演会
    • Place of Presentation
      富山
    • Year and Date
      2015-06-27
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Scleral and Choroidal Imaging.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2nd international conference of pathologic myopia (iPM)
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2015-06-20
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Definition of PM – followed by consensus discussion.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2nd international conference of pathologic myopia (iPM)
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2015-06-20
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Key Note Speech - What is the fundamental nature of PM? – a short excursion into histology, morphology and 3D anatomy.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      2nd international conference of pathologic myopia (iPM)
    • Place of Presentation
      Kyoto (Japan)
    • Year and Date
      2015-06-19
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Myopic maculopathy-update on its understanding and management.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      Update on high myopia and its associated disease.
    • Place of Presentation
      Taipei (Taiwan)
    • Year and Date
      2015-06-13
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Optic Disc Shape and Visual Field Defects in Eyes with Pathologic Myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      World Glaucoma Congress 2015.
    • Place of Presentation
      Hong Kong (China)
    • Year and Date
      2015-06-09
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Central corneal thickness.2015

    • Author(s)
      Suga M, Yoshida T, Aihara M, Ohno-Matsui K.
    • Organizer
      World Glaucoma Congress 2015.
    • Place of Presentation
      Hong Kong (China)
    • Year and Date
      2015-06-09
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] Updates on Myopic CNV.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      SNEC(Singapore National Eye Centre) 25th ANNIVERSARY INTERNATIONAL MEETING.
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2015-05-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Imaging & Management Decisions in Complications Associated with Pathological Myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      SNEC(Singapore National Eye Centre) 25th ANNIVERSARY INTERNATIONAL MEETING.
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2015-05-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Wide-field fundus imaging for pathologic myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      SNEC(Singapore National Eye Centre) 25th ANNIVERSARY INTERNATIONAL MEETING.
    • Place of Presentation
      Singapore (Singapore)
    • Year and Date
      2015-05-22
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] The role of Sirt1 for regulating VEGF in human RPE.2015

    • Author(s)
      Ishida T, Yoshida T, Shinohara K, Hongding L, KeJia C, Ohno-Matsui K.
    • Organizer
      ARVO 2015
    • Place of Presentation
      Denver (USA)
    • Year and Date
      2015-05-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research
  • [Presentation] 後部ぶどう腫と近視性網膜脈絡膜萎縮.2015

    • Author(s)
      大野京子.
    • Organizer
      第119回日本眼科学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-19
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視のOCTと病理所見の対比.2015

    • Author(s)
      大野京子.
    • Organizer
      第119回日本眼科学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-18
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] 病的近視の眼底病変.2015

    • Author(s)
      大野京子.
    • Organizer
      第119回日本眼科学会
    • Place of Presentation
      札幌
    • Year and Date
      2015-04-17
    • Related Report
      2015 Research-status Report
    • Invited
  • [Presentation] Lamina Cribrosa Changes in Myopia: Implications in Glaucoma Diagnosis and Monitoring.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      30th APAO(Asia-Pacific Academy of Ophthalmology).
    • Place of Presentation
      Guangzhou (China)
    • Year and Date
      2015-04-04
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Visual Outcomes in Patients with Myopic Choroidal Neovascularisation Receiving Intravitreal Aflibercept Injection.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      30th APAO(Asia-Pacific Academy of Ophthalmology).
    • Place of Presentation
      Guangzhou (China)
    • Year and Date
      2015-04-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Wide-Field Fundus Imaging of Pathologic Myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      30th APAO(Asia-Pacific Academy of Ophthalmology).
    • Place of Presentation
      Guangzhou (China)
    • Year and Date
      2015-04-02
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Presentation] Pathological Consequences of High Myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Organizer
      30th APAO(Asia-Pacific Academy of Ophthalmology).
    • Place of Presentation
      Guangzhou (China)
    • Year and Date
      2015-04-01
    • Related Report
      2015 Research-status Report
    • Int'l Joint Research / Invited
  • [Book] 専門医のための眼科診療クオリファイ28 近視の病態とマネジメント.2016

    • Author(s)
      大野京子.
    • Total Pages
      300
    • Publisher
      中山書店
    • Related Report
      2015 Research-status Report
  • [Book] Fundus Autofluorenscence in Pathological Myopia.2015

    • Author(s)
      Ohno-Matsui K.
    • Total Pages
      463
    • Publisher
      Wolters Kluwer
    • Related Report
      2015 Research-status Report
  • [Book] Myopia and Glaucoma.2015

    • Author(s)
      Ohno-Matsui K.
    • Total Pages
      113
    • Publisher
      Springer
    • Related Report
      2015 Research-status Report

URL: 

Published: 2015-04-16   Modified: 2019-03-29  

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