The analysis of skin-liver network during skin wound healing
| Project/Area Number |
15K15647
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Multi-year Fund |
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| Research Field |
Plastic surgery
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| Research Institution | Tohoku University |
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Principal Investigator |
Yamauchi Sakiko 東北大学, 医学系研究科, 非常勤講師 (10747091)
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| Co-Investigator(Kenkyū-buntansha) |
武田 睦 東北大学, 医学系研究科, 非常勤講師 (30333800)
館 正弘 東北大学, 医学系研究科, 教授 (50312004)
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| Co-Investigator(Renkei-kenkyūsha) |
KAWAKAMI KAZUYOSHI 東北大学, 大学院・医学系研究科, 教授 (10253973)
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| Research Collaborator |
KANNO EMI 東北大学, 大学院・医学系研究科, 講師 (10431595)
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| Project Period (FY) |
2015-04-01 – 2017-03-31
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| Project Status |
Completed (Fiscal Year 2016)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2016: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2015: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
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| Keywords | 創傷治癒学 / 臓器間ネットワーク |
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| Outline of Final Research Achievements |
Recently, the interaction between multiple organs and tissues have been clarified. However skin-liver network have not been reported. In the present study, we analyzed the network between skin and liver after wound creation.
Hepatic NKT cells and neutrophils were increased after wounding. In addition, MIP-2 expression was also increased after wounding. These results suggest that skin-liver network may be existed.
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Report
(3 results)
Research Products
(2 results)
