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Development of a novel injectable bioabsorbable implant substituted by adipose tissue in vivo

Research Project

Project/Area Number 15K15657
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeMulti-year Fund
Research Field Plastic surgery
Research InstitutionKansai Medical University

Principal Investigator

MORIMOTO Naoki  関西医科大学, 医学部, 准教授 (40378641)

Co-Investigator(Kenkyū-buntansha) 覚道 奈津子  関西医科大学, 医学部, 講師 (00509490)
伊藤 蘭  京都大学, 医学研究科, 特定病院助教 (00768921)
河合 勝也  京都大学, 医学研究科, 客員研究員 (90273458)
Co-Investigator(Renkei-kenkyūsha) YAMAOKA Tetsuji   (50243126)
Research Collaborator SAKAMOTO Yuki  グンゼ株式会社, QOL研究所
Project Period (FY) 2015-04-01 – 2018-03-31
Project Status Completed (Fiscal Year 2017)
Budget Amount *help
¥3,640,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥840,000)
Fiscal Year 2017: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2016: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2015: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Keywords吸収材料 / 脂肪 / 埋入
Outline of Final Research Achievements

We prepared the implants with collagen sponge (CS), using threads of either poly‐L‐lactide‐co‐ε‐caprolactone (PLACL) or poly‐L‐lactic acid (PLLA), and implanted them in the rat inguinal region.At 12 months after implantation, the internal space was maintained and the formation of adipose tissue was significantly promoted in the PLLA group.

Report

(4 results)
  • 2017 Annual Research Report   Final Research Report ( PDF )
  • 2016 Research-status Report
  • 2015 Research-status Report
  • Research Products

    (4 results)

All 2018 2017 2016

All Journal Article (1 results) (of which Peer Reviewed: 1 results) Presentation (3 results) (of which Int'l Joint Research: 1 results)

  • [Journal Article] Development of a novel bioabsorbable implant that is substituted by adipose tissue in vivo.2018

    • Author(s)
      Ogino S, Morimoto N, Sakamoto M, Jinno C, Yoshikawa K, Enoshiri T, Sakamoto Y, Taira T, Suzuki S.
    • Journal Title

      J Tissue Eng Regen Med

      Volume: 12 Issue: 3 Pages: 633-641

    • DOI

      10.1002/term.2482

    • Related Report
      2017 Annual Research Report
    • Peer Reviewed
  • [Presentation] 生体内で脂肪に置換される吸収材料の開発2017

    • Author(s)
      荻野秀一、森本尚樹、坂本道治、坂元悠紀、平嗣良、鈴木茂彦
    • Organizer
      第47回日本創傷治癒学会
    • Related Report
      2017 Annual Research Report
  • [Presentation] 生体で脂肪に置換される吸収性材料の開発2016

    • Author(s)
      荻野秀一 、森本尚樹 坂本道治 神野千鶴 坂元悠紀 鈴木茂彦
    • Organizer
      第25回日本形成外科学会基礎学術集会
    • Place of Presentation
      大阪(コングレコンベンションセンター)
    • Year and Date
      2016-09-15
    • Related Report
      2016 Research-status Report
  • [Presentation] The development of a novel bioabsorbable implant that is substituted by adipose tissue in vivo2016

    • Author(s)
      Shuichi Ogino, Naoki Morimoto, Michiharu Sakamoto, Chizuru Jinno, Yuki Sakamoto, Tsuguyoshi Taira, Shigehiko Suzuki,
    • Organizer
      the 2016 Tissue Engineering and Regenerative Medicine International Society- Asia Pacific Meeting
    • Place of Presentation
      台湾(台北市)
    • Year and Date
      2016-09-03
    • Related Report
      2016 Research-status Report
    • Int'l Joint Research

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Published: 2015-04-16   Modified: 2019-03-29  

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